Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 7/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 2/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24467779 | 0.86 | GPR119 (0.48) | GPR119ACACB | |
| SCHEMBL30877449 | 0.86 | GPR119 (0.53) | GPR119CHRM2CHRM1CHRM3ACACB | |
| SCHEMBL25309274 | 0.84 | GPR119 (0.52) | GPR119CHRM2CHRM1CHRM3ACACB | |
| SCHEMBL25309533 | 0.81 | GPR119 (0.59) | GPR119CHRM2CHRM1CHRM3HDAC1 | |
| SCHEMBL31271389 | 0.81 | GPR119 (0.59) | GPR119CHRM2CHRM1CHRM3ACACB | |
| SCHEMBL20456691 | 0.81 | GPR119 (0.59) | GPR119CHRM2CHRM1CHRM3HDAC1 | |
| SCHEMBL25310135 | 0.81 | GPR119 (0.59) | GPR119CHRM2CHRM1CHRM3ACACB | |
| SCHEMBL31271385 | 0.80 | GPR119 (0.58) | GPR119CHRM2CHRM1CHRM3HDAC1 | |
| SCHEMBL3579478 | 0.79 | GPR119 (0.59) | GPR119CHRM2CHRM1CHRM3HDAC1 | |
| SCHEMBL24962970 | 0.79 | GPR119 (0.57) | GPR119CHRM2CHRM1CHRM3ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157396-A | Pyridazinone derivatives and their use in medicine | 成都百裕制药股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| WO-2022111700-A1 | PYRIDAZINONE DERIVATIVES AND USE THEREOF IN MEDICINE | 成都百裕制药股份有限公司 | 2022-06-02 | — | — | WO | disclosed |
| WO-2022111700-A1 | PYRIDAZINONE DERIVATIVES AND USE THEREOF IN MEDICINE | 成都百裕制药股份有限公司 | 2022-06-02 | — | — | WO | disclosed |