Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 14/20 | 0.68 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.67 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.64 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.64 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.64 |
| ▸ | HTR2A | P28223 | 1/20 | 0.60 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.60 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.58 |
| ▸ | SPR | P35270 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27210131 | 1.00 | MPO (0.68) | MPOSLC6A4NOTUMMTNR1AMTNR1B | |
| SCHEMBL4487619 | 0.84 | MPO (0.65) | MPOSLC6A4HTR2ATRPM8HTR1A | |
| SCHEMBL14614196 | 0.83 | HTR2C (0.68) | SLC6A4NOTUMHTR2AHTR1AKMT2A | |
| SCHEMBL31292987 | 0.83 | MTNR1A (0.64) | SLC6A4MTNR1AMTNR1BHTR2ATRPM8 | |
| SCHEMBL2405001 | 0.81 | MPO (1.00) | MPOSLC6A4NOTUMMTNR1AMTNR1B | |
| SCHEMBL4492524 | 0.81 | MPO (0.67) | MPOSLC6A4HTR2ATRPM8HTR1A | |
| SCHEMBL2404396 | 0.81 | MPO (1.00) | MPOSLC6A4NOTUMMTNR1AMTNR1B | |
| SCHEMBL24693261 | 0.81 | MPO (0.69) | MPOSLC6A4NOTUMMTNR1AMTNR1B | |
| SCHEMBL8806539 | 0.81 | MPO (0.50) | MPOSLC6A4NOTUMMTNR1AMTNR1B | |
| SCHEMBL2403826 | 0.80 | MPO (1.00) | MPOSLC6A4NOTUMMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117957211-A | Fluorinated tryptamine compounds, analogs thereof, and methods of use thereof | 圣约瑟夫大学 | 2024-04-30 | — | — | CN | disclosed |