SCHEMBL3087790

SCHEMBL3087790

CC(=O)CCCCCCCCCCCCN1C(C)(C)CC2(CC1(C)C)NC(=O)NC2=O

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PAOX Q6QHF9 2/20 0.38
HTR2A P28223 6/20 0.36
HTR2C P28335 6/20 0.36
HTR2B P41595 6/20 0.36
CRBN Q96SW2 3/20 0.32
DDB1 Q16531 1/20 0.32
PDE4A P27815 1/20 0.32
PDE4B Q07343 1/20 0.32
PDE4C Q08493 1/20 0.32
PDE4D Q08499 1/20 0.32
BRD4 O60885 1/20 0.31
FPR3 P25089 1/20 0.31
FPR2 P25090 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9136570 0.78
SCHEMBL2976287 0.71 CRBN (0.36) CRBNDDB1
SCHEMBL2676051 0.65 CRBN (0.33) HTR2AHTR2CHTR2BCRBNDDB1
SCHEMBL14256466 0.65 CRBN (0.32) CRBNDDB1
SCHEMBL10151268 0.65 SSTR5 (0.33) CRBN
SCHEMBL18697241 0.65 MMP2 (0.38)
SCHEMBL18697245 0.65 MMP2 (0.38)
SCHEMBL11484816 0.64 CNR1 (0.48)
SCHEMBL7699126 0.64 CNR1 (0.48)
SCHEMBL11488928 0.64 CNR1 (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7790793-B2 Amide nucleating agent compositions CIBA SPECIALTY CHEM. CORP. (US) 2010-09-07 US disclosed
US-20070149663-A1 Resin compositions CIBA SPECIALTY CHEMICALS CORP. 2007-06-28 US disclosed
US-20070072979-A1 Dispersing agents in nanocomposites POLYMERS AUSTRALIA PTY, LIMITED (AU) 2007-03-29 US disclosed