SCHEMBL18697245

SCHEMBL18697245

CCCCCCCCCCCON1C(C)(C)CC2(CC1(C)C)NC(=O)NC2=O

nearest known ligand 0.43

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 6/20 0.38
MMP9 P14780 6/20 0.38
MMP3 P08254 2/20 0.38
TDP1 Q9NUW8 1/20 0.32
LMNA P02545 1/20 0.32
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MMP8 P22894 4/20 0.30
MMP13 P45452 4/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18697241 1.00 MMP2 (0.38) MMP2MMP9MMP3TDP1LMNA
SCHEMBL10151268 0.83 SSTR5 (0.33)
SCHEMBL10124607 0.76 NPC1 (0.32) MMP2MMP9MMP3NPC1RAB9A
SCHEMBL10124655 0.75 GAA (0.42) LMNANPC1RAB9ASMN1; SMN2
SCHEMBL10124652 0.75 GAA (0.42) LMNANPC1RAB9ASMN1; SMN2
SCHEMBL2676051 0.75 CRBN (0.33)
SCHEMBL10124620 0.74 MMP2 (0.30) MMP2MMP9MMP3
SCHEMBL2814613 0.73 MAPT (0.36) MMP2MMP9MMP3SMN1; SMN2
SCHEMBL1001848 0.73 MAPT (0.36) MMP2MMP9MMP3SMN1; SMN2
SCHEMBL1828803 0.73 MAPT (0.36) MMP2MMP9MMP3SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2440557-B1 NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS BASF SE (DE) 2017-04-05 EP disclosed