SCHEMBL3087798

SCHEMBL3087798

Cc1ccc(N([C]=S)c2ccc(C)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.48
TSHR P16473 4/20 0.48
ACHE P22303 6/20 0.42
TDP1 Q9NUW8 1/20 0.42
MAPT P10636 1/20 0.35
MCOLN3 Q8TDD5 1/20 0.35
CYP2C19 P33261 1/20 0.35
CYP2A6 P11509 1/20 0.35
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
CHRNA7 P36544 1/20 0.32
POLB P06746 1/20 0.31
HSD17B1 P14061 1/20 0.31
HSD17B2 P37059 1/20 0.31
RAB9A P51151 1/20 0.31
LMNA P02545 1/20 0.30
ALOX12 P18054 1/20 0.30
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11823858 0.77 ALDH1A1 (0.52) ALDH1A1TSHRACHETDP1MAPT
SCHEMBL3094965 0.74 LMNA (0.42) ALDH1A1TSHRTDP1MAPTCYP2A6
SCHEMBL3087692 0.74 CYP2A6 (0.42) ALDH1A1TDP1CYP2A6ALOX15
SCHEMBL2140337 0.74 ALDH1A1 (0.48) ALDH1A1TSHRACHETDP1MAPT
SCHEMBL2858411 0.72 ALDH1A1 (0.39) ALDH1A1TDP1MAPTCYP2C19CA1
SCHEMBL10001341 0.72 ALDH1A1 (0.46) ALDH1A1TSHRACHETDP1MAPT
SCHEMBL330780 0.69 ALDH1A1 (0.42) ALDH1A1TSHRACHETDP1MAPT
SCHEMBL16982395 0.67 ALDH1A1 (0.61) ALDH1A1TSHRACHETDP1MAPT
SCHEMBL7486403 0.67 ALDH1A1 (0.61) ALDH1A1TSHRACHETDP1MAPT
SCHEMBL6123161 0.67 ALDH1A1 (0.61) ALDH1A1TSHRACHETDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100233415-A1 OPTICAL RECORDING MEDIUM AND AZO METAL CHELATE COMPOUND MITSUI CHEMICALS, INC. (JP) 2010-09-16 US disclosed
EP-1997856-A1 OPTICAL RECORDING MEDIUM AND AZO METAL CHELATE COMPOUND Mitsui Chemicals, Inc. (JP) 2008-12-03 EP disclosed