Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 18/20 | 0.47 |
| ▸ | BRD4 | O60885 | 4/20 | 0.47 |
| ▸ | CCNC | P24863 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 2/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19643965 | 1.00 | CREBBP (0.47) | CREBBPBRD4CCNCCDK8EP300 | |
| SCHEMBL19663100 | 0.88 | CREBBP (0.39) | CREBBPBRD4CCNCCDK8AXL | |
| SCHEMBL19660413 | 0.86 | CREBBP (0.47) | CREBBPBRD4CCNCCDK8EP300 | |
| SCHEMBL21237550 | 0.85 | CREBBP (0.47) | CREBBPBRD4EP300 | |
| SCHEMBL19663200 | 0.85 | CREBBP (0.47) | CREBBPBRD4EP300 | |
| SCHEMBL21237382 | 0.83 | CREBBP (0.45) | CREBBPBRD4EP300 | |
| SCHEMBL21419225 | 0.83 | CREBBP (0.49) | CREBBPBRD4EP300 | |
| SCHEMBL24368131 | 0.81 | CREBBP (0.44) | CREBBPBRD4EP300 | |
| SCHEMBL30878068 | 0.77 | CREBBP (0.42) | CREBBPBRD4EP300 | |
| SCHEMBL19643357 | 0.77 | CREBBP (0.42) | CREBBPBRD4EP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112165944-B | Imidazopiperazine inhibitors of transcriptional activator proteins | 德州大学系统董事会 | 2024-04-09 | — | — | CN | disclosed |