Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 7/20 | 0.64 |
| ▸ | FGFR1 | P11362 | 7/20 | 0.64 |
| ▸ | WEE1 | P30291 | 6/20 | 0.57 |
| ▸ | IGF1R | P08069 | 5/20 | 0.52 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 2/20 | 0.45 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.44 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.44 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30878805 | 0.88 | EGFR (0.56) | EGFRFGFR1WEE1IGF1RLRRK2 | |
| SCHEMBL30878354 | 0.86 | IGF1R (0.60) | EGFRIGF1RLRRK2PTK2SRC | |
| SCHEMBL30878366 | 0.85 | FGFR1 (0.66) | EGFRFGFR1WEE1SRCFGFR2 | |
| SCHEMBL30878465 | 0.85 | WEE1 (0.77) | EGFRFGFR1WEE1SRCFGFR2 | |
| SCHEMBL30878347 | 0.85 | EGFR (0.61) | EGFRFGFR1WEE1IGF1RLRRK2 | |
| SCHEMBL30878436 | 0.85 | EGFR (0.49) | EGFRFGFR1WEE1IGF1RLRRK2 | |
| SCHEMBL30878328 | 0.80 | EGFR (0.50) | EGFRFGFR1WEE1IGF1RLRRK2 | |
| SCHEMBL30878310 | 0.79 | EGFR (0.65) | EGFRFGFR1WEE1IGF1RLRRK2 | |
| SCHEMBL30878321 | 0.78 | EGFR (0.54) | EGFRFGFR1WEE1IGF1RLRRK2 | |
| SCHEMBL5762573 | 0.78 | FGFR1 (1.00) | EGFRFGFR1WEE1SRCFGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4612148-A1 | 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE AND 7-AMINO-1-PYRIMIDO[4,5-D]PYRIMIDIN-2(1 H)-ONE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER | Cancer Research Technology Limited (GB) | 2025-09-10 | — | — | EP | claimed |
| WO-2024094963-A1 | 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE AND 7-AMINO-1-PYRIMIDO[4,5-D]PYRIMIDIN-2(1 H)-ONE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-05-10 | — | — | WO | claimed |
| EP-4612148-A1 | 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE AND 7-AMINO-1-PYRIMIDO[4,5-D]PYRIMIDIN-2(1 H)-ONE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER | Cancer Research Technology Limited (GB) | 2025-09-10 | — | — | EP | disclosed |
| WO-2024094963-A1 | 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE AND 7-AMINO-1-PYRIMIDO[4,5-D]PYRIMIDIN-2(1 H)-ONE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-05-10 | — | — | WO | disclosed |