Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18296386 | 0.87 | MAPT (0.59) | MEN1KMT2AMAPTSIRT6ALDH1A1 | |
| SCHEMBL23104698 | 0.80 | MAPT (0.56) | MEN1KMT2AMAPTSIRT6ALDH1A1 | |
| SCHEMBL28901607 | 0.80 | MEN1 (0.66) | MEN1KMT2AMAPTSIRT6ALDH1A1 | |
| SCHEMBL30878667 | 0.80 | MEN1 (0.59) | MEN1KMT2AMAPTSIRT6ALDH1A1 | |
| SCHEMBL1647379 | 0.80 | KMT2A (0.62) | MEN1KMT2AMAPTSIRT6ALDH1A1 | |
| SCHEMBL4336239 | 0.78 | L3MBTL3 (0.69) | MEN1KMT2AMAPTSIRT6ALDH1A1 | |
| SCHEMBL22489080 | 0.78 | MEN1 (0.64) | MEN1KMT2AMAPTSIRT6ALDH1A1 | |
| SCHEMBL4191910 | 0.78 | SIRT6 (0.72) | MEN1KMT2AMAPTSIRT6ALDH1A1 | |
| SCHEMBL77340 | 0.77 | MAPT (0.71) | MEN1KMT2AMAPTSIRT6ALDH1A1 | |
| SCHEMBL3574460 | 0.77 | MAPT (0.71) | MEN1KMT2AMAPTSIRT6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4612148-A1 | 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE AND 7-AMINO-1-PYRIMIDO[4,5-D]PYRIMIDIN-2(1 H)-ONE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER | Cancer Research Technology Limited (GB) | 2025-09-10 | — | — | EP | disclosed |
| WO-2024094963-A1 | 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE AND 7-AMINO-1-PYRIMIDO[4,5-D]PYRIMIDIN-2(1 H)-ONE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-05-10 | — | — | WO | disclosed |