Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | WDR5 | P61964 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30879071 | 0.83 | NSD2 (0.48) | ALDH1A1SMN1; SMN2NPSR1GAAKMT2A | |
| SCHEMBL10126983 | 0.81 | HTT (0.64) | ALDH1A1CYP1A2CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL30878986 | 0.80 | HTT (0.55) | ALDH1A1CYP1A2CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL30921338 | 0.78 | WDR5 (0.54) | ALDH1A1HTTCYP2D6GAAWDR5 | |
| SCHEMBL30879299 | 0.78 | KMT2A (0.44) | ALDH1A1KMT2APOLBMEN1NPY1R | |
| SCHEMBL30878757 | 0.77 | ALDH1A1 (0.76) | ALDH1A1CYP1A2CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL15486931 | 0.76 | HTT (0.67) | ALDH1A1CYP1A2CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL30879164 | 0.74 | CYP19A1 (0.54) | ALDH1A1CYP1A2CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL30879141 | 0.73 | WDR5 (0.61) | ALDH1A1HTTCYP2D6GAAWDR5 | |
| SCHEMBL29354408 | 0.73 | ALDH1A1 (0.58) | ALDH1A1CYP1A2CYP3A4CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4612148-A1 | 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE AND 7-AMINO-1-PYRIMIDO[4,5-D]PYRIMIDIN-2(1 H)-ONE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER | Cancer Research Technology Limited (GB) | 2025-09-10 | — | — | EP | disclosed |
| WO-2024094963-A1 | 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE AND 7-AMINO-1-PYRIMIDO[4,5-D]PYRIMIDIN-2(1 H)-ONE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-05-10 | — | — | WO | disclosed |