Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.48 |
| ▸ | WDR5 | P61964 | 7/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30878762 | 0.83 | ALDH1A1 (0.50) | ALDH1A1WDR5GAAKMT2APOLB | |
| SCHEMBL30878705 | 0.83 | WDR5 (0.64) | ALDH1A1WDR5GAACYP2D6 | |
| SCHEMBL30878681 | 0.81 | ALDH1A1 (0.45) | ALDH1A1WDR5GAAKMT2APOLB | |
| SCHEMBL30879355 | 0.80 | WDR5 (0.62) | ALDH1A1WDR5GAAKMT2ACYP2D6 | |
| SCHEMBL1971542 | 0.79 | ALDH1A1 (0.57) | ALDH1A1WDR5GAAKMT2APOLB | |
| SCHEMBL30878953 | 0.77 | ALDH1A1 (0.53) | ALDH1A1WDR5GAAKMT2APOLB | |
| SCHEMBL2014034 | 0.77 | HTT (0.53) | ALDH1A1WDR5GAAKMT2APOLB | |
| SCHEMBL30879275 | 0.76 | MEN1 (0.45) | ALDH1A1GAAKMT2APOLBLMNA | |
| SCHEMBL1968454 | 0.76 | ALDH1A1 (0.60) | ALDH1A1WDR5GAAKMT2APOLB | |
| SCHEMBL26655887 | 0.76 | ALDH1A1 (0.55) | ALDH1A1WDR5GAAKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4612148-A1 | 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE AND 7-AMINO-1-PYRIMIDO[4,5-D]PYRIMIDIN-2(1 H)-ONE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER | Cancer Research Technology Limited (GB) | 2025-09-10 | — | — | EP | disclosed |
| WO-2024094963-A1 | 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE AND 7-AMINO-1-PYRIMIDO[4,5-D]PYRIMIDIN-2(1 H)-ONE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-05-10 | — | — | WO | disclosed |