SCHEMBL30879495

SCHEMBL30879495

O=Cc1ccc(Oc2ccc(C(F)(F)F)cc2)c(CO)c1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 5/20 0.46
HTR2A P28223 2/20 0.43
KCNH2 Q12809 2/20 0.43
SLC6A2 P23975 1/20 0.43
SLC6A3 Q01959 1/20 0.43
FFAR1 O14842 2/20 0.40
L3MBTL1 Q9Y468 3/20 0.40
ALDH1A1 P00352 1/20 0.40
POLB P06746 1/20 0.40
TTR P02766 1/20 0.40
MAPT P10636 2/20 0.39
LMNA P02545 1/20 0.39
ATM Q13315 1/20 0.39
SCN9A Q15858 4/20 0.39
RAB9A P51151 1/20 0.39
KDM4E B2RXH2 1/20 0.38
EPAS1 Q99814 1/20 0.38
HRH3 Q9Y5N1 1/20 0.38
PTGS1 P23219 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15909890 0.80 TTR (0.43) SLC6A4HTR2AKCNH2SLC6A2SLC6A3
SCHEMBL26936527 0.78 TTR (0.67) L3MBTL1ALDH1A1TTRMAPTLMNA
SCHEMBL25369932 0.77 KDM4E (0.43) L3MBTL1ALDH1A1POLBMAPTKDM4E
SCHEMBL30694815 0.77 APP (0.41) ALDH1A1POLBRAB9AKDM4E
SCHEMBL25369618 0.77 APP (0.41) ALDH1A1POLBRAB9AKDM4E
SCHEMBL14656246 0.76 ESRRA (0.46) TTRSCN9A
SCHEMBL184377 0.76 PARP10 (0.50) L3MBTL1ALDH1A1POLBLMNAKDM4E
SCHEMBL24181290 0.74 L3MBTL1 (0.46) SLC6A4HTR2AKCNH2FFAR1L3MBTL1
SCHEMBL15278091 0.74 L3MBTL1 (0.58) SLC6A4HTR2AKCNH2L3MBTL1ALDH1A1
SCHEMBL11309119 0.73 FFAR1 (0.57) SLC6A4HTR2AKCNH2FFAR1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250346549-A2 NOVEL AROMATIC MOLECULES Xeniopro GmbH (DE) 2025-11-13 US disclosed
US-20250084023-A2 NOVEL AROMATIC MOLECULES Xeniopro GmbH (DE) 2025-03-13 US disclosed
US-20240140895-A1 NOVEL AROMATIC MOLECULES Xeniopro GmbH (DE) 2024-05-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250084023-A2 NOVEL AROMATIC MOLECULES AHR, TYR, MUSK SLC6A4 3966/4885HTR2A 3292/4885KCNH2 3431/4885
US-20250346549-A2 NOVEL AROMATIC MOLECULES AHR, TYR, MUSK SLC6A4 3966/4885HTR2A 3292/4885KCNH2 3431/4885
US-20240140895-A1 NOVEL AROMATIC MOLECULES AHR, TYR, MUSK SLC6A4 3966/4885HTR2A 3292/4885KCNH2 3431/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.