SCHEMBL30879520

SCHEMBL30879520

Nc1cc2c(c(N)c1N)Nc1ccccc1O2

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 11/20 0.53
HTR2B P41595 2/20 0.40
HTR7 P34969 1/20 0.40
GAA P10253 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
DHODH Q02127 1/20 0.36
MAPT P10636 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
ALDH1A1 P00352 1/20 0.35
POLB P06746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3984907 0.82 ALOX5 (0.57) ALOX5HTR2BHTR7GAANPSR1
SCHEMBL89676 0.77 ALOX5 (0.59) ALOX5HTR2BHTR7GAANPSR1
SCHEMBL31191625 0.77 ALOX5 (0.59) ALOX5HTR2BHTR7GAANPSR1
SCHEMBL28757942 0.75 ALOX5 (0.44) ALOX5HTR2BHTR7MAPTL3MBTL1
Hydrochloric Acid SCHEMBL27849245 0.75 ALOX5 (0.57) ALOX5HTR2BHTR7GAANPSR1
Hydrochloric Acid SCHEMBL4195457 0.75 ALOX5 (0.57) ALOX5HTR2BHTR7GAANPSR1
SCHEMBL28350006 0.73 ALOX5 (0.50) ALOX5HTR2BHTR7GAANPSR1
SCHEMBL28399952 0.73 ALOX5 (0.46) ALOX5HTR2BHTR7GAANPSR1
SCHEMBL1673283 0.72 ALOX5 (0.48) ALOX5HTR2BHTR7GAANPSR1
Phenoxazine SCHEMBL6310178 0.72 ALOX5 (1.00) ALOX5HTR2BHTR7GAANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117843899-A Preparation method of two-dimensional covalent organic framework material based on 10- (4-aminobenzene) -phenoxazine-3, 7-diamine and photolytic water application 南京工业大学 2024-04-09 CN disclosed