Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 11/20 | 0.48 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28543913 | 0.91 | ALOX5 (0.50) | ALOX5HTR2BHTR7MEN1KMT2A | |
| SCHEMBL3984907 | 0.85 | ALOX5 (0.57) | ALOX5HTR2BHTR7DHODHMEN1 | |
| SCHEMBL5847281 | 0.77 | ALOX5 (0.50) | ALOX5HTR2BHTR7DHODHMEN1 | |
| SCHEMBL31191625 | 0.76 | ALOX5 (0.59) | ALOX5HTR2BHTR7DHODHMEN1 | |
| SCHEMBL89676 | 0.76 | ALOX5 (0.59) | ALOX5HTR2BHTR7DHODHMEN1 | |
| Hydrochloric Acid SCHEMBL27849245 | 0.75 | ALOX5 (0.57) | ALOX5HTR2BHTR7DHODHMEN1 | |
| Hydrochloric Acid SCHEMBL4195457 | 0.75 | ALOX5 (0.57) | ALOX5HTR2BHTR7DHODHMEN1 | |
| SCHEMBL27822363 | 0.74 | ALOX5 (0.47) | ALOX5HTR2BHTR7DHODHMEN1 | |
| SCHEMBL121074 | 0.73 | ALOX5 (0.55) | ALOX5DHODHGAANPSR1ALDH1A1 | |
| SCHEMBL31191628 | 0.73 | ALOX5 (0.55) | ALOX5DHODHGAANPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140179901-A1 | Peptide Conjugates and Fluorescence Detection Methods for Intracellular Caspase Assay | APPLIED BIOSYSTEMS, LLC (US) | 2014-06-26 | — | — | US | disclosed |
| US-20140179901-A1 | Peptide Conjugates and Fluorescence Detection Methods for Intracellular Caspase Assay | APPLIED BIOSYSTEMS, LLC (US) | 2014-06-26 | — | — | US | disclosed |
| US-8623995-B2 | Peptide conjugates and fluorescence detection methods for intracellular caspase assay | APPLIED BIOSYSTEMS, LLC (US) | 2014-01-07 | — | — | US | disclosed |
| US-8623995-B2 | Peptide conjugates and fluorescence detection methods for intracellular caspase assay | APPLIED BIOSYSTEMS, LLC (US) | 2014-01-07 | — | — | US | disclosed |
| US-20110097758-A1 | Peptide Conjugates and Fluorescence Detection Methods for Intracellular Caspase Assay | Life Technologies Corporation (US) | 2011-04-28 | — | — | US | disclosed |
| US-20110097758-A1 | Peptide Conjugates and Fluorescence Detection Methods for Intracellular Caspase Assay | Life Technologies Corporation (US) | 2011-04-28 | — | — | US | disclosed |
| US-20100273943-A1 | PEPTIDE CONJUGATES AND FLUORESCENCE DETECTION METHODS FOR INTRACELLULAR CASPASE ASSAY | Life Technologies Corporation (US) | 2010-10-28 | — | — | US | disclosed |
| US-20100273943-A1 | PEPTIDE CONJUGATES AND FLUORESCENCE DETECTION METHODS FOR INTRACELLULAR CASPASE ASSAY | Life Technologies Corporation (US) | 2010-10-28 | — | — | US | disclosed |
| US-20070009440-A1 | Peptide Conjugates and Fluorescence Detection Methods for Intarcellular Caspase Assay | APPLERA CORPORATION (US) | 2007-01-11 | — | — | US | disclosed |
| US-20070009440-A1 | Peptide Conjugates and Fluorescence Detection Methods for Intarcellular Caspase Assay | APPLERA CORPORATION (US) | 2007-01-11 | — | — | US | disclosed |
| US-20060252109-A1 | Peptide conjugates and fluorescence detection methods for intracellular caspase assay | APPLERA CORPORATION (US) | 2006-11-09 | — | — | US | disclosed |
| US-20060252109-A1 | Peptide conjugates and fluorescence detection methods for intracellular caspase assay | APPLERA CORPORATION (US) | 2006-11-09 | — | — | US | disclosed |
| US-6979530-B2 | Peptide conjugates and fluorescence detection methods for intracellular caspase assay | APPLERA CORPORATION (US) | 2005-12-27 | — | — | US | disclosed |
| US-6979530-B2 | Peptide conjugates and fluorescence detection methods for intracellular caspase assay | APPLERA CORPORATION (US) | 2005-12-27 | — | — | US | disclosed |
| WO-2002094778-A3 | PEPTIDE CONJUGATES AND FLUORESCENCE DETECTION METHODS FOR INTRACELLULAR CASPASE ASSAY | APPLERA CORP (US) | 2004-02-19 | — | — | WO | disclosed |
| US-20030186214-A1 | Dibenzorhodamine dyes and diamino-benzophenoxazine dyes for | APPLIED BIOSYSTEMS, LLC | 2003-10-02 | — | — | US | disclosed |
| US-20030186214-A1 | Dibenzorhodamine dyes and diamino-benzophenoxazine dyes for | APPLIED BIOSYSTEMS, LLC | 2003-10-02 | — | — | US | disclosed |
| WO-2002094778-A2 | PEPTIDE CONJUGATES AND FLUORESCENCE DETECTION METHODS FOR INTRACELLULAR CASPASE ASSAY | APPLERA CORPORATION (US) | 2002-11-28 | — | — | WO | disclosed |
| WO-2002094778-A2 | PEPTIDE CONJUGATES AND FLUORESCENCE DETECTION METHODS FOR INTRACELLULAR CASPASE ASSAY | APPLERA CORPORATION (US) | 2002-11-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140179901-A1 | Peptide Conjugates and Fluorescence Detection Methods for Intracellular Caspase Assay | CASP5, CASP7, CASP12 | ALOX5 2008/4885HTR2B 3132/4885HTR7 1440/4885 |
| US-20070009440-A1 | Peptide Conjugates and Fluorescence Detection Methods for Intarcellular Caspase Assay | CASP5, CASP12, CASP3 | ALOX5 1663/4885HTR2B 2630/4885HTR7 1203/4885 |
| US-20060252109-A1 | Peptide conjugates and fluorescence detection methods for intracellular caspase assay | CASP5, CASP7, CASP12 | ALOX5 2008/4885HTR2B 3132/4885HTR7 1440/4885 |
| US-20100273943-A1 | PEPTIDE CONJUGATES AND FLUORESCENCE DETECTION METHODS FOR INTRACELLULAR CASPASE ASSAY | CASP5, CASP7, CASP12 | ALOX5 2008/4885HTR2B 3132/4885HTR7 1440/4885 |
| US-20030186214-A1 | Dibenzorhodamine dyes and diamino-benzophenoxazine dyes for | BAD, CASP5, PDCD5 | ALOX5 1513/4885HTR2B 2588/4885HTR7 1103/4885 |
| US-20110097758-A1 | Peptide Conjugates and Fluorescence Detection Methods for Intracellular Caspase Assay | CASP5, CASP7, CASP12 | ALOX5 2008/4885HTR2B 3132/4885HTR7 1440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.