Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 4/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29216643 | 1.00 | KDM4E (0.68) | KDM4EHSD17B10ALDH1A1GAAPOLB | |
| SCHEMBL19291349 | 0.88 | KDM4E (0.72) | KDM4EHSD17B10ALDH1A1GAAPOLB | |
| SCHEMBL15818889 | 0.84 | ALDH1A1 (0.49) | KDM4EHSD17B10ALDH1A1GAAPOLB | |
| SCHEMBL30542908 | 0.84 | ALDH1A1 (0.49) | KDM4EHSD17B10ALDH1A1GAAPOLB | |
| SCHEMBL11217216 | 0.84 | HSD17B10 (0.53) | KDM4EHSD17B10ALDH1A1GAAPOLB | |
| SCHEMBL4433893 | 0.84 | KDM4E (0.77) | KDM4EHSD17B10ALDH1A1GAAPOLB | |
| SCHEMBL3085306 | 0.83 | MAPT (0.51) | KDM4EHSD17B10ALDH1A1GAAL3MBTL1 | |
| SCHEMBL11908425 | 0.82 | NPC1 (0.71) | KDM4EHSD17B10ALDH1A1GAAPOLB | |
| SCHEMBL15777997 | 0.81 | SMN1; SMN2 (0.70) | KDM4EHSD17B10ALDH1A1GAAPOLB | |
| SCHEMBL3636284 | 0.81 | ALDH1A1 (0.46) | KDM4EHSD17B10ALDH1A1GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117843590-A | 3-amino-4- (piperazin-1-yl) benzamide derivative, pharmaceutical composition containing same, and preparation method and application thereof | 中国药科大学 | 2024-04-09 | — | — | CN | claimed |
| CN-117843590-A | 3-amino-4- (piperazin-1-yl) benzamide derivative, pharmaceutical composition containing same, and preparation method and application thereof | 中国药科大学 | 2024-04-09 | — | — | CN | disclosed |
| CN-117843590-A | 3-amino-4- (piperazin-1-yl) benzamide derivative, pharmaceutical composition containing same, and preparation method and application thereof | 中国药科大学 | 2024-04-09 | — | — | CN | disclosed |
| CN-117843590-A | 3-amino-4- (piperazin-1-yl) benzamide derivative, pharmaceutical composition containing same, and preparation method and application thereof | 中国药科大学 | 2024-04-09 | — | — | CN | disclosed |