Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.72 |
| ▸ | GAA | P10253 | 3/20 | 0.72 |
| ▸ | POLB | P06746 | 3/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.72 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 3/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.43 |
| ▸ | KDM5C | P41229 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29216643 | 0.88 | KDM4E (0.68) | KDM4EHSD17B10GAAPOLBTDP1 | |
| SCHEMBL30879532 | 0.88 | KDM4E (0.68) | KDM4EHSD17B10GAAPOLBTDP1 | |
| SCHEMBL11908425 | 0.85 | NPC1 (0.71) | KDM4EHSD17B10GAAPOLBTDP1 | |
| SCHEMBL7423568 | 0.85 | KDM4E (0.97) | KDM4EHSD17B10GAAPOLBTDP1 | |
| SCHEMBL29805515 | 0.84 | KDM4E (1.00) | KDM4EHSD17B10GAAPOLBTDP1 | |
| SCHEMBL27950425 | 0.83 | MYC (0.51) | KDM4EHSD17B10GAAPOLBTDP1 | |
| SCHEMBL2307303 | 0.83 | ADRB1 (0.50) | KDM4EHSD17B10GAAPOLBTDP1 | |
| Hydrochloric Acid SCHEMBL10318583 | 0.81 | ADRB1 (0.49) | KDM4EHSD17B10GAAPOLBTDP1 | |
| SCHEMBL2302437 | 0.81 | MAPT (0.51) | KDM4EHSD17B10GAAPOLBTDP1 | |
| SCHEMBL2303906 | 0.81 | HSD17B10 (0.55) | KDM4EHSD17B10GAAPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2734517-B1 | BENZAMIDES | MERCK PATENT GMBH (DE) | 2017-08-30 | — | — | EP | disclosed |