Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | VDR | P11473 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
| ▸ | P4HB | P07237 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17842030 | 1.00 | DYRK1A (0.45) | DYRK1ACLK4ROCK1TAAR1AHR | |
| Hydrochloric Acid SCHEMBL17842300 | 0.98 | ROCK1 (0.44) | DYRK1ACLK4ROCK1TAAR1AHR | |
| SCHEMBL11722266 | 0.83 | AHR (0.54) | CLK4ROCK1AHRSLC6A2SLC6A4 | |
| SCHEMBL29518433 | 0.82 | DYRK1A (0.45) | DYRK1ACLK4AHRAOC3DRD2 | |
| SCHEMBL17842130 | 0.82 | DYRK1A (0.45) | DYRK1ACLK4AHRAOC3DRD2 | |
| SCHEMBL28557150 | 0.82 | SLC6A3 (0.64) | DYRK1ACLK4AHRDRD2SLC6A2 | |
| SCHEMBL30879852 | 0.82 | AOC3 (0.42) | DYRK1ACLK4ROCK1TAAR1AOC3 | |
| SCHEMBL30638827 | 0.82 | SLC6A3 (0.64) | DYRK1ACLK4AHRDRD2SLC6A2 | |
| SCHEMBL17842041 | 0.81 | GRM5 (0.43) | DYRK1ASLC6A2SLC6A4SLC6A3GRM5 | |
| SCHEMBL29588451 | 0.81 | DYRK1A (0.44) | DYRK1ACLK4AHRDRD2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024092222-A1 | MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR D AND RELATED PRODUCTS AND METHODS | ESCIENT PHARMACEUTICALS, INC. (US) | 2024-05-02 | — | — | WO | disclosed |