Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | VDR | P11473 | 1/20 | 0.44 |
| ▸ | P4HB | P07237 | 1/20 | 0.43 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 2/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17842300 | 0.82 | ROCK1 (0.44) | DYRK1ACLK4VDRP4HBSLC10A1 | |
| SCHEMBL17842030 | 0.81 | DYRK1A (0.45) | DYRK1ACLK4VDRP4HBSLC10A1 | |
| SCHEMBL17842130 | 0.81 | DYRK1A (0.45) | DYRK1ACLK4VDRP4HBSLC10A1 | |
| SCHEMBL28557150 | 0.81 | SLC6A3 (0.64) | DYRK1ACLK4VDRP4HBSLC10A1 | |
| SCHEMBL30879872 | 0.81 | DYRK1A (0.45) | DYRK1ACLK4VDRP4HBSLC10A1 | |
| SCHEMBL30638827 | 0.81 | SLC6A3 (0.64) | DYRK1ACLK4VDRP4HBSLC10A1 | |
| SCHEMBL29518433 | 0.81 | DYRK1A (0.45) | DYRK1ACLK4VDRP4HBSLC10A1 | |
| SCHEMBL17858535 | 0.77 | DYRK1A (0.42) | DYRK1ACLK4VDRP4HBSLC10A1 | |
| SCHEMBL7546358 | 0.74 | PBRM1 (0.46) | DYRK1ACLK4VDRSLC10A1DRD2 | |
| SCHEMBL28662969 | 0.72 | CASR (0.61) | CLK4VDRP4HBDRD2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111559976-B | Synthetic method of heteroaryl thioether | 扬州大学 | 2022-05-13 | — | — | CN | disclosed |