Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30880032 | 1.00 | NR4A2 (0.41) | NR4A2MAPTALDH1A1RAB9AKDM4E | |
| SCHEMBL30880042 | 0.89 | SMN1; SMN2 (0.42) | NR4A2MAPTALDH1A1RAB9AKDM4E | |
| SCHEMBL30880013 | 0.88 | NR4A2 (0.40) | NR4A2ALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL35211913 | 0.82 | CYP4A11 (0.35) | NR4A2CREBBPNPC1 | |
| SCHEMBL35211910 | 0.82 | CYP4A11 (0.35) | NR4A2CREBBPNPC1 | |
| SCHEMBL35211571 | 0.82 | CYP4A11 (0.35) | NR4A2CREBBPNPC1 | |
| SCHEMBL31342430 | 0.79 | CYP4A11 (0.39) | NR4A2NPC1 | |
| SCHEMBL35212509 | 0.79 | AR (0.34) | MAPTALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL35212228 | 0.79 | AR (0.34) | MAPTALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL30937357 | 0.78 | PRKAB2 (0.44) | MAPTALDH1A1RAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025090412-A1 | DCAF1 LIGANDS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2025-05-01 | — | — | WO | disclosed |
| WO-2024092011-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2024-05-02 | — | — | WO | disclosed |