Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.36 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.36 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.36 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30937357 | 0.90 | PRKAB2 (0.44) | SMN1; SMN2NPSR1TP53CA1CA2 | |
| SCHEMBL30880032 | 0.89 | NR4A2 (0.41) | SMN1; SMN2NPSR1NR4A2HPGDALDH1A1 | |
| SCHEMBL30880033 | 0.89 | NR4A2 (0.41) | SMN1; SMN2NPSR1NR4A2HPGDALDH1A1 | |
| SCHEMBL30880013 | 0.88 | NR4A2 (0.40) | NR4A2ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL35211913 | 0.80 | CYP4A11 (0.35) | NR4A2NPC1 | |
| SCHEMBL35211571 | 0.80 | CYP4A11 (0.35) | NR4A2NPC1 | |
| SCHEMBL35211910 | 0.80 | CYP4A11 (0.35) | NR4A2NPC1 | |
| SCHEMBL31342430 | 0.79 | CYP4A11 (0.39) | NR4A2NPC1 | |
| SCHEMBL31342605 | 0.78 | CYP3A4 (0.33) | CYP2C9CYP2C19 | |
| SCHEMBL35212509 | 0.77 | AR (0.34) | NPSR1CA1CA2HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4608807-A1 | PROTEIN DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2025-09-03 | — | — | EP | disclosed |
| WO-2025090412-A1 | DCAF1 LIGANDS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2025-05-01 | — | — | WO | disclosed |
| WO-2024092009-A1 | PROTEIN DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2024-05-02 | — | — | WO | disclosed |
| WO-2024092011-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2024-05-02 | — | — | WO | disclosed |