Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 3/20 | 0.57 |
| ▸ | ACACA | Q13085 | 2/20 | 0.57 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23578433 | 0.81 | ACACB (0.57) | ACACBACACAMITFTP53NCOA3 | |
| SCHEMBL30880252 | 0.81 | ACACB (0.56) | ACACBACACAMITFTP53NCOA3 | |
| SCHEMBL23588077 | 0.77 | ACACB (0.52) | ACACBACACAMITFTP53NCOA3 | |
| SCHEMBL23578438 | 0.77 | ACACB (0.64) | ACACBACACAMITFTP53NCOA3 | |
| SCHEMBL30880261 | 0.76 | ACACB (0.51) | ACACBACACAMITFTP53NCOA3 | |
| SCHEMBL13926724 | 0.75 | ACACB (0.65) | ACACBACACAMITFTP53NCOA3 | |
| SCHEMBL7295131 | 0.74 | ACACB (0.97) | ACACBACACAMITFTP53NCOA3 | |
| SCHEMBL26027547 | 0.73 | ACACB (0.61) | ACACBACACAS1PR1S1PR3NPC1 | |
| SCHEMBL23588315 | 0.73 | TP53 (0.50) | ACACBACACAMITFTP53NCOA3 | |
| SCHEMBL35210439 | 0.71 | S1PR1 (0.67) | ACACBACACATP53S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024089421-A1 | TETRAZOLE DERIVATIVES | SITRYX THERAPEUTICS LIMITED (GB) | 2024-05-02 | — | — | WO | disclosed |