Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 3/20 | 0.56 |
| ▸ | ACACA | Q13085 | 2/20 | 0.56 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23578433 | 0.90 | ACACB (0.57) | ACACBACACAMITFTP53NCOA3 | |
| SCHEMBL23578438 | 0.85 | ACACB (0.64) | ACACBACACAMITFTP53NCOA3 | |
| SCHEMBL23588077 | 0.85 | ACACB (0.52) | ACACBACACAMITFTP53NCOA3 | |
| SCHEMBL23588315 | 0.81 | TP53 (0.50) | ACACBACACAMITFTP53NCOA3 | |
| SCHEMBL30880266 | 0.81 | ACACB (0.57) | ACACBACACAMITFTP53NCOA3 | |
| SCHEMBL23588220 | 0.77 | FFAR1 (0.46) | ACACBACACAMITFTP53NCOA3 | |
| SCHEMBL27291369 | 0.77 | MITF (0.43) | ACACBACACAMITFTP53NCOA3 | |
| SCHEMBL27291464 | 0.76 | NPC1 (0.41) | ACACBACACAMITFTP53NCOA3 | |
| SCHEMBL30880261 | 0.75 | ACACB (0.51) | ACACBACACAMITFTP53NCOA3 | |
| SCHEMBL23588141 | 0.75 | GSTP1 (0.43) | ACACBACACAMITFTP53NCOA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024089421-A1 | TETRAZOLE DERIVATIVES | SITRYX THERAPEUTICS LIMITED (GB) | 2024-05-02 | — | — | WO | disclosed |