SCHEMBL30880299

SCHEMBL30880299

c1ccc(Cn2cccc2)nc1

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.52
KMT2A Q03164 2/20 0.52
MEN1 O00255 1/20 0.52
PKM P14618 1/20 0.52
CYP1A2 P05177 1/20 0.47
CYP2C19 P33261 1/20 0.47
HRH1 P35367 1/20 0.47
MAPT P10636 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
LIN28A Q9H9Z2 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
LMNA P02545 1/20 0.45
DDB1 Q16531 1/20 0.44
CRBN Q96SW2 1/20 0.44
KDM4C Q9H3R0 1/20 0.43
GABRA1 P14867 1/20 0.43
GABRA5 P31644 1/20 0.43
HRH3 Q9Y5N1 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7475272 1.00 ALDH1A1 (0.52) ALDH1A1KMT2AMEN1PKMCYP1A2
SCHEMBL9594114 0.84 ALDH1A1 (0.54) ALDH1A1KMT2AMEN1PKMCYP1A2
SCHEMBL12841354 0.81 ALDH1A1 (0.50) ALDH1A1KMT2AMEN1PKMCYP1A2
SCHEMBL2716739 0.80 CYP11B1 (0.59) CYP1A2MAPT
SCHEMBL31408151 0.80 CYP11B1 (0.59) CYP1A2MAPT
SCHEMBL27494735 0.79 HSD17B10 (0.54) ALDH1A1CYP1A2HRH1LMNAHRH3
SCHEMBL19260079 0.78 MAPT (0.47) ALDH1A1KMT2AMEN1PKMCYP1A2
SCHEMBL15499470 0.75 PON1 (0.51) ALDH1A1KMT2AMEN1PKMCYP1A2
SCHEMBL17457945 0.75 ALDH1A1 (0.53) ALDH1A1KMT2AMEN1PKMCYP1A2
SCHEMBL1333260 0.74 CYP1A2 (0.71) ALDH1A1KMT2ACYP1A2CYP2C19HRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117820255-A Application of catalyst and degradation method of ester substance 上海科技大学 2024-04-05 CN disclosed