Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30880299 | 1.00 | ALDH1A1 (0.52) | ALDH1A1KMT2AMEN1PKMCYP1A2 | |
| SCHEMBL9594114 | 0.84 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1PKMCYP1A2 | |
| SCHEMBL12841354 | 0.81 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1PKMCYP1A2 | |
| SCHEMBL2716739 | 0.80 | CYP11B1 (0.59) | CYP1A2MAPT | |
| SCHEMBL31408151 | 0.80 | CYP11B1 (0.59) | CYP1A2MAPT | |
| SCHEMBL27494735 | 0.79 | HSD17B10 (0.54) | ALDH1A1CYP1A2HRH1LMNAHRH3 | |
| SCHEMBL19260079 | 0.78 | MAPT (0.47) | ALDH1A1KMT2AMEN1PKMCYP1A2 | |
| SCHEMBL15499470 | 0.75 | PON1 (0.51) | ALDH1A1KMT2AMEN1PKMCYP1A2 | |
| SCHEMBL17457945 | 0.75 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1PKMCYP1A2 | |
| SCHEMBL1333260 | 0.74 | CYP1A2 (0.71) | ALDH1A1KMT2ACYP1A2CYP2C19HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101678011-A | Spiro-indolinone compounds | MERCK & CO INC | 2010-03-24 | — | — | CN | claimed |
| CN-115057894-B | Environment-friendly drier, and preparation method and application thereof | 上海佰奥聚新材料科技有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-117820255-A | Application of catalyst and degradation method of ester substance | 上海科技大学 | 2024-04-05 | — | — | CN | disclosed |
| CN-115057894-A | Environment-friendly drier, preparation method and application | 上海佰奥聚新材料科技有限公司 | 2022-09-16 | — | — | CN | disclosed |
| CN-104903320-B | Nitrogen-containing heterocycle compound or its salt | 富士胶片株式会社 | 2018-11-13 | — | — | CN | disclosed |
| CN-107011341-A | 1H-pyrrolo [2,3-b ] pyridine derivatives and their use as kinase inhibitors | 沃纳利斯(R&D)有限公司 | 2017-08-04 | — | — | CN | disclosed |
| CN-106866658-A | 1H-pyrrolo [2,3-b ] pyridine derivatives and their use as kinase inhibitors | 沃纳利斯(R&D)有限公司 | 2017-06-20 | — | — | CN | disclosed |
| US-20130096334-A1 | Magnetic Nanoparticle-Supported Glutathione as a Sustainable Organocatalyst | The United States of America as represented by the Administrator of the United States Environment Pr (US) | 2013-04-18 | — | — | US | disclosed |
| US-20130096334-A1 | Magnetic Nanoparticle-Supported Glutathione as a Sustainable Organocatalyst | The United States of America as represented by the Administrator of the United States Environment Pr (US) | 2013-04-18 | — | — | US | disclosed |
| US-8324125-B2 | Magnetic nanoparticle-supported glutathione as a sustainable organocatalyst | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE U.S. ENVIRONMENTAL PROTECTION AGENCY (US) | 2012-12-04 | — | — | US | disclosed |
| US-20110054180-A1 | Magnetic Nanoparticle-Supported Glutathione as a Sustainable Organocatalyst | USA as Represented by the Administrator of U.S. Environmental Protection Agency (US) | 2011-03-03 | — | — | US | disclosed |
| US-20110054180-A1 | Magnetic Nanoparticle-Supported Glutathione as a Sustainable Organocatalyst | USA as Represented by the Administrator of U.S. Environmental Protection Agency (US) | 2011-03-03 | — | — | US | disclosed |
| CN-101678011-A | Spiro-indolinone compounds | MERCK & CO INC | 2010-03-24 | — | — | CN | disclosed |
| EP-1246799-A1 | SUBSTITUTED PYRROLE MANNICH BASES TO COMBAT PAIN AND ALLERGIC REACTIONS | Grünenthal GmbH (DE) | 2002-10-09 | — | — | EP | disclosed |
| WO-2001047878-A1 | SUBSTITUTED PYRROLE MANNICH BASES TO COMBAT PAIN AND ALLERGIC REACTIONS | Grünenthal GmbH (DE) | 2001-07-05 | — | — | WO | disclosed |
| WO-2001047882-A2 | SUBSTANCE LIBRARY WHICH CAN BE OBTAINED BY REACTING ALDEHYDES WITH SECONDARY AMINES, ACID CHLORIDES AND NAPHTHOL, PYRROLE AND/OR INDOLE COMPOUNDS | Grünenthal GmbH (DE) | 2001-07-05 | — | — | WO | disclosed |
| US-4511575-A | Antidiabetic pyrrolecarboxylic acids | PFIZER INC. (US) | 1985-04-16 | — | — | US | disclosed |
| US-4511576-A | Antidiabetic pyrrolecarboxylic acids | PFIZER INC. (US) | 1985-04-16 | — | — | US | disclosed |
| US-4351843-A | LOWERING BLOOD GLUCOSE | PFIZER INC. (US) | 1982-09-28 | — | — | US | disclosed |
| US-4282242-A | HYPOGLYCEMIC AGENTS | PFIZER INC. (US) | 1981-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110054180-A1 | Magnetic Nanoparticle-Supported Glutathione as a Sustainable Organocatalyst | GSTK1, GSTA1, GSTP1 | ALDH1A1 281/4885KMT2A 932/4885MEN1 804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.