Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.47 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NNMT | P40261 | 3/20 | 0.36 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL149886 | 1.00 | DGAT1 (0.47) | DGAT1ERN1JAK2BTKALDH1A1 | |
| SCHEMBL31690101 | 0.82 | SMN1; SMN2 (0.33) | DGAT1ALDH1A1MAPTTDP1HPGD | |
| SCHEMBL29562032 | 0.82 | EPRS1 (0.40) | ALDH1A1KDM4E | |
| SCHEMBL206341 | 0.82 | EPRS1 (0.40) | ALDH1A1KDM4E | |
| SCHEMBL28221345 | 0.82 | DGAT1 (0.52) | DGAT1ERN1JAK2BTKALDH1A1 | |
| SCHEMBL3117625 | 0.82 | ERN1 (0.47) | DGAT1ERN1JAK2BTKALDH1A1 | |
| SCHEMBL29196743 | 0.80 | TDP1 (0.41) | DGAT1ALDH1A1MAPTNNMTSIRT3 | |
| SCHEMBL18150159 | 0.79 | DGAT1 (0.32) | DGAT1HPGD | |
| SCHEMBL16122584 | 0.78 | DGAT1 (0.48) | DGAT1ERN1JAK2BTKALDH1A1 | |
| SCHEMBL17818478 | 0.78 | ERN1 (0.44) | DGAT1ERN1JAK2BTKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117820218-B | Preparation method of apatamide and intermediate | 江苏希迪制药有限公司 | 2025-05-27 | — | — | CN | disclosed |
| CN-117820218-A | Preparation method of apatamide and intermediate | 江苏希迪制药有限公司 | 2024-04-05 | — | — | CN | disclosed |