SCHEMBL30880435

SCHEMBL30880435

O=C1CCSc2cccc(C(F)(F)F)c21

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
VHL P40337 1/20 0.36
ELOC Q15369 1/20 0.36
ELOB Q15370 1/20 0.36
HTR2C P28335 13/20 0.35
HTR2B P41595 13/20 0.35
HTR2A P28223 12/20 0.35
KDM4E B2RXH2 1/20 0.33
HTT P42858 1/20 0.33
TNF P01375 1/20 0.33
IL6 P05231 1/20 0.33
TP53 P04637 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30880421 1.00 ALDH1A1 (0.40) ALDH1A1L3MBTL1VHLELOCELOB
SCHEMBL24188888 0.75 ALDH1A1 (0.44) ALDH1A1L3MBTL1VHLELOCELOB
SCHEMBL2156971 0.74 KDM4E (0.39) ALDH1A1VHLELOCELOBKDM4E
SCHEMBL9404887 0.74 VHL (0.39) ALDH1A1VHLELOCELOBKDM4E
SCHEMBL23861131 0.74 MAOA (0.44) ALDH1A1L3MBTL1VHLELOCELOB
SCHEMBL8822554 0.74 VHL (0.39) ALDH1A1VHLELOCELOBKDM4E
SCHEMBL8472833 0.74 VHL (0.46) ALDH1A1VHLELOCELOBKDM4E
SCHEMBL3827464 0.72 HTR2C (0.40) HTR2CHTR2BHTR2ATNFIL6
SCHEMBL29515304 0.70 ALDH1A1 (0.53) ALDH1A1VHLELOCELOBKDM4E
SCHEMBL29565791 0.69 ALDH1A1 (0.42) ALDH1A1L3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112939958-B Condensed ring acyl compound and application thereof 沈阳中化农药化工研发有限公司 2024-05-14 CN disclosed