Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 10/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | THPO | P40225 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.48 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.48 |
| ▸ | ITGAL | P20701 | 1/20 | 0.48 |
| ▸ | MARK3 | P27448 | 1/20 | 0.47 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7372104 | 1.00 | PGR (0.65) | PGRALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL12997888 | 1.00 | PGR (0.65) | PGRALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL31913 | 0.84 | PGR (0.49) | PGRALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL29388768 | 0.84 | PGR (0.49) | PGRALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL27478508 | 0.84 | PGR (0.70) | PGRMEN1KMT2AITGB2ICAM1 | |
| SCHEMBL9140974 | 0.82 | ALDH1A1 (0.50) | PGRALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL22861629 | 0.81 | PGR (0.46) | PGRALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL26149613 | 0.80 | PGR (0.51) | PGRALDH1A1MEN1KMT2AITGB2 | |
| SCHEMBL10948887 | 0.80 | ELANE (0.63) | PGRALDH1A1MARK3ELANE | |
| SCHEMBL13341351 | 0.78 | PGR (0.53) | PGRALDH1A1MEN1KMT2AITGB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117567350-A | Preparation method of indolone compound | 暨南大学 | 2024-02-20 | — | — | CN | disclosed |