Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 5/20 | 0.38 |
| ▸ | HTR2C | P28335 | 5/20 | 0.38 |
| ▸ | DAO | P14920 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28345272 | 1.00 | NOTUM (0.40) | NOTUMKMT2AHTR2AHTR2CDAO | |
| SCHEMBL23799363 | 0.82 | KMT2A (0.40) | NOTUMKMT2AHTR2AHTR2CDAO | |
| SCHEMBL34463705 | 0.77 | KMT2A (0.38) | KMT2AHTR2AHTR2CALDH1A1KDM4E | |
| SCHEMBL17522841 | 0.72 | PIK3CA (0.41) | MAPTDRD3 | |
| SCHEMBL1170864 | 0.71 | FTO (0.35) | — | |
| SCHEMBL14765140 | 0.71 | HTR2A (0.31) | KMT2AHTR2AHTR2CADRA2A | |
| SCHEMBL9259549 | 0.70 | HTR2A (0.44) | NOTUMKMT2AHTR2AHTR2CDAO | |
| SCHEMBL6697572 | 0.70 | NOTUM (0.40) | NOTUMKMT2AHTR2AHTR2CDAO | |
| SCHEMBL7396812 | 0.69 | RPS6KA3 (0.43) | NOTUMKMT2AHTR2AHTR2CADRA2A | |
| SCHEMBL9387355 | 0.68 | HTR2A (0.41) | NOTUMKMT2AHTR2AHTR2CL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113135929-B | Furopyridone amide compound, preparation method and application thereof | 江西济民可信集团有限公司 | 2024-04-19 | — | — | CN | disclosed |