Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.42 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30882397 | 1.00 | NOTUM (0.50) | NOTUMCA12CA1CA2CA7 | |
| SCHEMBL30882564 | 0.85 | CA12 (0.56) | NOTUMCA12CA1CA2CA7 | |
| SCHEMBL30882491 | 0.85 | CA12 (0.56) | NOTUMCA12CA1CA2CA7 | |
| SCHEMBL14012580 | 0.84 | NOTUM (0.64) | NOTUMCA12CA1CA2CA7 | |
| SCHEMBL752590 | 0.84 | NOTUM (0.64) | NOTUMCA12CA1CA2CA7 | |
| SCHEMBL20043300 | 0.81 | NOTUM (0.51) | NOTUMCA12CA1CA2CA7 | |
| SCHEMBL30882517 | 0.81 | NOTUM (0.73) | NOTUMCA12CA1CA2CA7 | |
| SCHEMBL30882506 | 0.77 | NOTUM (0.46) | NOTUMCA12CA1CA2CA7 | |
| SCHEMBL30882575 | 0.77 | NOTUM (0.46) | NOTUMCA12CA1CA2CA7 | |
| SCHEMBL29244637 | 0.75 | NOTUM (0.60) | NOTUMCA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117903077-B | Dihydrooxadiazinone compound and application thereof | 上海超阳药业有限公司 | 2024-09-03 | — | — | CN | disclosed |
| CN-117903077-A | Dihydrooxadiazinon compound and application thereof | 上海超阳药业有限公司 | 2024-04-19 | — | — | CN | disclosed |