Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30882506 | 1.00 | NOTUM (0.46) | NOTUMKDM4ECA12CA1CA2 | |
| SCHEMBL29723291 | 0.86 | L3MBTL1 (0.45) | ALDH1A1MAPTTSHR | |
| SCHEMBL23412483 | 0.86 | L3MBTL1 (0.45) | ALDH1A1MAPTTSHR | |
| SCHEMBL30882499 | 0.83 | NOTUM (0.66) | NOTUMKDM4ECA12CA1CA2 | |
| SCHEMBL31306436 | 0.81 | MAPT (0.43) | ALDH1A1MEN1KMT2AMAPTTSHR | |
| SCHEMBL752590 | 0.79 | NOTUM (0.64) | NOTUMKDM4ECA12CA1CA2 | |
| SCHEMBL14012580 | 0.79 | NOTUM (0.64) | NOTUMKDM4ECA12CA1CA2 | |
| SCHEMBL29723251 | 0.79 | LMNA (0.43) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL23411878 | 0.79 | LMNA (0.43) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL2543756 | 0.79 | CA12 (0.53) | NOTUMKDM4ECA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117903077-B | Dihydrooxadiazinone compound and application thereof | 上海超阳药业有限公司 | 2024-09-03 | — | — | CN | disclosed |
| CN-117903077-A | Dihydrooxadiazinon compound and application thereof | 上海超阳药业有限公司 | 2024-04-19 | — | — | CN | disclosed |