Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.64 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.52 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.52 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.52 |
| ▸ | P4HB | P07237 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | XDH | P47989 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.47 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14012580 | 1.00 | NOTUM (0.64) | NOTUMTAS1R3TAS1R1TAS1R2P4HB | |
| SCHEMBL20043300 | 0.86 | NOTUM (0.51) | NOTUMCA12CA1CA2CA7 | |
| SCHEMBL3830811 | 0.86 | NOTUM (0.69) | NOTUMP4HBCA12CA1CA2 | |
| SCHEMBL1997248 | 0.86 | NOTUM (0.73) | NOTUMP4HBCA12CA1CA2 | |
| SCHEMBL10907300 | 0.84 | NOTUM (0.66) | NOTUMP4HBCA12CA1CA2 | |
| SCHEMBL30882425 | 0.84 | NOTUM (0.50) | NOTUMP4HBCA12CA1CA2 | |
| SCHEMBL30882397 | 0.84 | NOTUM (0.50) | NOTUMP4HBCA12CA1CA2 | |
| SCHEMBL30208027 | 0.83 | TAS1R3 (0.48) | NOTUMTAS1R3TAS1R1TAS1R2CA12 | |
| SCHEMBL10861732 | 0.83 | NOTUM (0.64) | NOTUMP4HBCA12CA1CA2 | |
| SCHEMBL399738 | 0.83 | P4HB (0.66) | NOTUMP4HBCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4696748-A1 | PERFLUOROPOLYETHER GEL CURABLE COMPOSITION, PERFLUOROPOLYETHER GEL CURED PRODUCT, AND ELECTRONIC COMPONENT SEALED WITH SAID CURED PRODUCT | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2026-02-18 | — | — | EP | disclosed |
| US-12545761-B2 | Photocurable fluoropolyether-based elastomer composition and bonding method thereof | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2026-02-10 | — | — | US | disclosed |
| US-20260034252-A1 | FIBROBLAST ACTIVATION PROTEIN-TARGETED COMPOSITIONS AND METHODS OF USE THEREOF | RATIO THERAPEUTICS INC (US) | 2026-02-05 | — | — | US | disclosed |
| EP-4561998-A1 | FIBROBLAST ACTIVATION PROTEIN-TARGETED COMPOSITIONS AND METHODS OF USE THEREOF | Ratio Therapeutics, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| WO-2024214452-A1 | PERFLUOROPOLYETHER GEL CURABLE COMPOSITION, PERFLUOROPOLYETHER GEL CURED PRODUCT, AND ELECTRONIC COMPONENT SEALED WITH SAID CURED PRODUCT | 信越化学工業株式会社 | 2024-10-17 | — | — | WO | disclosed |
| CN-117840009-A | Method for forming coating film of photocurable fluoropolyether elastomer composition | 信越化学工业株式会社 | 2024-04-09 | — | — | CN | disclosed |
| WO-2024026072-A1 | FIBROBLAST ACTIVATION PROTEIN-TARGETED COMPOSITIONS AND METHODS OF USE THEREOF | RATIO THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |
| WO-2024026072-A1 | FIBROBLAST ACTIVATION PROTEIN-TARGETED COMPOSITIONS AND METHODS OF USE THEREOF | RATIO THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |
| CN-113165012-B | Method for forming coating film of photocurable fluoropolyether elastomer composition | 信越化学工业株式会社 | 2024-01-30 | — | — | CN | disclosed |
| US-11634391-B2 | Compounds which are inhibitors of Notum | UCL BUSINESS LTD (GB) | 2023-04-25 | — | — | US | disclosed |
| CN-1057760-C | Amino acid-substituted benzoylguanidines, a process for their preparation, their use as a medicament or diagnostic agent and a medicament containing them | HOECHST AG (DE) | 2000-10-25 | — | — | CN | disclosed |
| US-6057322-A | USEFUL IN TREATMENT OF CARDIOVASCULAR DISEASES | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-05-02 | — | — | US | disclosed |
| US-6022899-A | EFFECTIVE INHIBITORS OF THE CELLULAR SODIUM PROTON ANTIPORTER | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-02-08 | — | — | US | disclosed |
| US-5753710-A | INHIBITORS OF THE CELLULAR SODIUM PROTON ANTIPORTER | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-05-19 | — | — | US | disclosed |
| US-5708034-A | FOR TREATING ARRHYTHMIA, ISCHEMIA | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-13 | — | — | US | disclosed |
| US-5665739-A | CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-09-09 | — | — | US | disclosed |
| CN-1155538-A | Substituted imidogen sulfamide, its preparation, use and medicines containing the same | HOECHST AG (DE) | 1997-07-30 | — | — | CN | disclosed |
| US-5641792-A | CARDIOTONIC AGENTS, ALSO FOR STROKES AND NERVOUS SYSTEM DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-06-24 | — | — | US | disclosed |
| US-5631293-A | CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-20 | — | — | US | disclosed |
| CN-1137035-A | Basic group substituted benzoyl guanidine, its preparing process, its use as medicine or diagnostic reagent, and medicine containing the same | HOECHST AG (DE) | 1996-12-04 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11634391-B2 | Compounds which are inhibitors of Notum | NOTUM, GOT2, GOT1 | NOTUM 1/4885TAS1R3 4367/4885TAS1R1 3381/4885 |
| US-12545761-B2 | Photocurable fluoropolyether-based elastomer composition and bonding method thereof | RAD51, FRG1, COL2A1 | NOTUM 4592/4885TAS1R3 884/4885TAS1R1 334/4885 |
| US-20260034252-A1 | FIBROBLAST ACTIVATION PROTEIN-TARGETED COMPOSITIONS AND METHODS OF USE THEREOF | CCR6, OGFRL1, IL6ST | NOTUM 4300/4885TAS1R3 3500/4885TAS1R1 3527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.