SCHEMBL30883192

SCHEMBL30883192

N#CN(c1cccc([N+](=O)[O-])c1)c1cccc([N+](=O)[O-])c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.55
LMNA P02545 1/20 0.55
ALDH1A1 P00352 10/20 0.51
KMT2A Q03164 5/20 0.51
MAPT P10636 4/20 0.51
MEN1 O00255 4/20 0.51
MAPK1 P28482 1/20 0.51
NPSR1 Q6W5P4 1/20 0.48
TDP1 Q9NUW8 2/20 0.47
ACHE P22303 1/20 0.47
ALOX15 P16050 1/20 0.47
NPC1 O15118 1/20 0.47
CASP3 P42574 1/20 0.47
RAB9A P51151 1/20 0.47
SENP8 Q96LD8 1/20 0.47
SENP7 Q9BQF6 1/20 0.47
SENP6 Q9GZR1 1/20 0.47
HSP90AA1 P07900 1/20 0.46
POLB P06746 1/20 0.46
GAA P10253 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27864504 0.83 ALDH1A1 (0.47) TSHRLMNAALDH1A1KMT2AMAPT
SCHEMBL8824675 0.83 ALDH1A1 (0.56) TSHRLMNAALDH1A1KMT2AMAPT
Dinitrophenylene SCHEMBL27485048 0.77 TSHR (0.77) TSHRLMNAALDH1A1KMT2AMAPT
Dinitrophenylene SCHEMBL28186803 0.76 TSHR (0.94) TSHRLMNAALDH1A1KMT2ATDP1
Dinitrophenylene SCHEMBL27324143 0.76 TSHR (0.94) TSHRLMNAALDH1A1KMT2ATDP1
SCHEMBL30780918 0.76 TSHR (0.61) TSHRLMNAALDH1A1KMT2AMAPT
SCHEMBL1413129 0.76 TSHR (0.61) TSHRLMNAALDH1A1KMT2AMAPT
Dinitrophenylene SCHEMBL28121404 0.75 TSHR (0.74) TSHRLMNAALDH1A1KMT2ATDP1
SCHEMBL9007543 0.74 ALDH1A1 (0.47) TSHRLMNAALDH1A1KMT2AMAPT
SCHEMBL12100862 0.74 ALDH1A1 (0.69) TSHRLMNAALDH1A1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117736059-A Green preparation method of N, N-disubstituted urea and derivative 宁夏大学 2024-03-22 CN disclosed