Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.57 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1413129 | 1.00 | TSHR (0.61) | TSHRLMNAALDH1A1MAPTMEN1 | |
| SCHEMBL14397069 | 0.85 | TSHR (0.57) | TSHRLMNAALDH1A1MAPTMEN1 | |
| SCHEMBL11819373 | 0.85 | TSHR (0.57) | TSHRLMNAALDH1A1MAPTMEN1 | |
| SCHEMBL12048735 | 0.83 | ABCG2 (0.59) | TSHRLMNAALDH1A1MAPTMEN1 | |
| SCHEMBL12550512 | 0.82 | ALDH1A1 (0.54) | TSHRLMNAALDH1A1MAPTMEN1 | |
| SCHEMBL2035403 | 0.82 | ALDH1A1 (0.54) | TSHRLMNAALDH1A1MAPTMEN1 | |
| SCHEMBL10651901 | 0.82 | ALDH1A1 (0.57) | TSHRLMNAALDH1A1MAPTMEN1 | |
| SCHEMBL13716196 | 0.82 | ALDH1A1 (0.54) | TSHRLMNAALDH1A1MAPTMEN1 | |
| SCHEMBL4959484 | 0.80 | ATM (0.55) | TSHRLMNAALDH1A1MAPTMEN1 | |
| SCHEMBL3412211 | 0.80 | ALDH1A1 (0.52) | TSHRLMNAALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024030651-A1 | GPX4 INHIBITORS AND USE THEREOF | SONATA THERAPEUTICS, INC. (US) | 2024-02-08 | — | — | WO | disclosed |