Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | ELANE | P08246 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | F7 | P08709 | 1/20 | 0.45 |
| ▸ | F3 | P13726 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29350345 | 0.82 | ALDH1A1 (0.66) | ALDH1A1THRBKMT2AL3MBTL1TDP1 | |
| SCHEMBL3654895 | 0.82 | ALDH1A1 (0.66) | ALDH1A1THRBKMT2AL3MBTL1TDP1 | |
| Ethane SCHEMBL28042096 | 0.81 | ALDH1A1 (0.64) | ALDH1A1THRBKMT2AL3MBTL1TDP1 | |
| SCHEMBL25295776 | 0.81 | ALDH1A1 (0.64) | ALDH1A1THRBKMT2AL3MBTL1TDP1 | |
| SCHEMBL1927639 | 0.81 | ALDH1A1 (0.64) | ALDH1A1THRBKMT2AL3MBTL1TDP1 | |
| SCHEMBL26520508 | 0.80 | ELANE (0.68) | ALDH1A1ELANEKMT2AL3MBTL1TDP1 | |
| SCHEMBL25258813 | 0.80 | ALDH1A1 (0.62) | ALDH1A1THRBKMT2AL3MBTL1TDP1 | |
| SCHEMBL28065703 | 0.78 | ALDH1A1 (0.60) | ALDH1A1THRBKMT2AL3MBTL1TDP1 | |
| SCHEMBL28374928 | 0.77 | ALDH1A1 (0.58) | ALDH1A1THRBKMT2AL3MBTL1TDP1 | |
| SCHEMBL14168881 | 0.77 | ALDH1A1 (0.58) | ALDH1A1THRBKMT2AL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11963964-B2 | Small molecules for mouse satellite cell proliferation | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2024-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11963964-B2 | Small molecules for mouse satellite cell proliferation | MKI67, MYLK2, MYH2 | ALDH1A1 2684/4885ELANE 3797/4885THRB 3028/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.