Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 4/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 2/20 | 0.39 |
| ▸ | ACE | P12821 | 2/20 | 0.39 |
| ▸ | CPA1 | P15085 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | REN | P00797 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 2/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Leucine SCHEMBL27478083 | 0.88 | CTNNB1 (0.41) | PSMB5CTNNB1MMP2MMP9MMP8 | |
| Leucine SCHEMBL2294646 | 0.85 | CTNNB1 (0.39) | PSMB5CTNNB1MMP2MMP9MMP8 | |
| Leucine SCHEMBL27470090 | 0.85 | CTNNB1 (0.39) | PSMB5CTNNB1MMP2MMP9MMP8 | |
| SCHEMBL30885174 | 0.84 | CTNNB1 (0.52) | CTNNB1MMP9MMP8MMEACE | |
| SCHEMBL2295176 | 0.83 | PSMB5 (0.47) | PSMB5CTNNB1MMP2MMP9MMP8 | |
| Hydrochloric Acid SCHEMBL2297582 | 0.82 | PSMB5 (0.47) | PSMB5CTNNB1MMP2MMP9MMP8 | |
| Alanine SCHEMBL671385 | 0.81 | PSMB5 (0.46) | PSMB5CTNNB1MMP2MMP9MMP8 | |
| Levacetylleucine SCHEMBL6674776 | 0.76 | PSMB5 (0.48) | PSMB5MMP2MMP9MMP8MME | |
| Leucine SCHEMBL27471555 | 0.74 | MAPT (0.47) | PSMB5CTNNB1MMEACECPA1 | |
| SCHEMBL233988 | 0.73 | MMP2 (0.48) | PSMB5MMP2MMP9MMP8MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030003583-A1 | Regulation of transgene expression following AAV transduction | CHILDREN'S HOSPITAL RESEARCH FOUNDATION | 2003-01-02 | — | — | US | disclosed |