Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 12/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.44 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30885400 | 0.89 | STING1 (0.47) | STING1TRPV1MAPT | |
| SCHEMBL30885386 | 0.86 | STING1 (0.58) | STING1TRPV1KDM4EALDH1A1MAPT | |
| SCHEMBL30885447 | 0.82 | STING1 (0.51) | STING1TRPV1CLK1DYRK1AHTT | |
| SCHEMBL30885458 | 0.82 | STING1 (0.53) | STING1HTTKDM4EMAPT | |
| SCHEMBL30885399 | 0.81 | STING1 (0.52) | STING1KDM4EALDH1A1MAPT | |
| SCHEMBL30885437 | 0.78 | STING1 (0.58) | STING1HTTALDH1A1 | |
| SCHEMBL30885395 | 0.77 | STING1 (0.44) | STING1KDM4E | |
| SCHEMBL30386673 | 0.76 | STING1 (0.72) | STING1TRPV1HTTMAPT | |
| SCHEMBL28991332 | 0.76 | STING1 (0.72) | STING1TRPV1HTTMAPT | |
| SCHEMBL30885376 | 0.76 | STING1 (0.46) | STING1TRPV1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117756698-A | Urea compound and medical application thereof as STING inhibitor | 中国药科大学 | 2024-03-26 | — | — | CN | disclosed |