Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 13/20 | 0.52 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MPO | P05164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30885386 | 0.94 | STING1 (0.58) | STING1KCNK2MAPTKIF11KDM4E | |
| SCHEMBL30885459 | 0.89 | STING1 (0.51) | STING1KCNK2SNCA | |
| SCHEMBL30885458 | 0.89 | STING1 (0.53) | STING1MAPTKDM4E | |
| SCHEMBL30885437 | 0.85 | STING1 (0.58) | STING1KCNK2KIF11ALDH1A1 | |
| SCHEMBL30885428 | 0.85 | STING1 (0.55) | STING1MAPTKDM4EALDH1A1TSHR | |
| SCHEMBL30885433 | 0.83 | STING1 (0.53) | STING1MAPTKDM4EALDH1A1MPO | |
| SCHEMBL30885389 | 0.82 | STING1 (0.57) | STING1KCNK2KIF11ALDH1A1 | |
| SCHEMBL28991301 | 0.82 | STING1 (0.57) | STING1KCNK2KIF11 | |
| SCHEMBL30885429 | 0.82 | STING1 (0.51) | STING1KIF11ALDH1A1 | |
| SCHEMBL30387111 | 0.82 | STING1 (0.57) | STING1KCNK2KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117756698-A | Urea compound and medical application thereof as STING inhibitor | 中国药科大学 | 2024-03-26 | — | — | CN | disclosed |