SCHEMBL30886155

SCHEMBL30886155

COc1c(Br)cc2c(c1Cl)OCc1c(C(=O)O)nn(-c3cc(Cl)cc(Cl)c3)c1-2

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ CCNA2 P20248 4/20 0.38
▸ CDK2 P24941 4/20 0.38
▸ CCNA1 P78396 4/20 0.38
▸ CYP1A2 P05177 1/20 0.32
▸ HIF1A Q16665 1/20 0.32
▸ PIK3CD O00329 5/20 0.31
▸ PIK3R2 O00459 5/20 0.31
▸ PIK3CA P42336 5/20 0.31
▸ PIK3CB P42338 5/20 0.31
▸ PIK3CG P48736 5/20 0.31
▸ PIK3R5 Q8WYR1 5/20 0.31
▸ PIK3R3 Q92569 5/20 0.31
▸ PTGS2 P35354 1/20 0.31
▸ RAD52 P43351 1/20 0.31
▸ ALDH1A1 P00352 1/20 0.30
▸ L3MBTL1 Q9Y468 1/20 0.30
▸ HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30886066 0.88 CCNA2 (0.42) CCNA2CDK2CCNA1RAD52ALDH1A1
SCHEMBL30885988 0.83 PIK3CD (0.34) PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG
SCHEMBL30885869 0.82 CCNA2 (0.39) CCNA2CDK2CCNA1CYP1A2HIF1A
SCHEMBL17381608 0.82 CCNA2 (0.39) CCNA2CDK2CCNA1CYP1A2HIF1A
SCHEMBL17385520 0.77 CYP1A2 (0.35) CCNA2CDK2CCNA1CYP1A2HIF1A
SCHEMBL30759474 0.77 MAPT (0.34) CCNA2CDK2CCNA1CYP1A2HIF1A
SCHEMBL27117850 0.77 MAPT (0.34) CCNA2CDK2CCNA1CYP1A2HIF1A
SCHEMBL31236976 0.76 CCNA2 (0.39) CCNA2CDK2CCNA1CYP1A2HIF1A
SCHEMBL31236979 0.76 CCNA2 (0.39) CCNA2CDK2CCNA1CYP1A2HIF1A
SCHEMBL30759577 0.75 CCNA2 (0.43) CCNA2CDK2CCNA1CYP1A2HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4598928-A1 FOLLICLE-STIMULATING HORMONE RECEPTOR (FSHR) TARGETED THERAPEUTICS AND USES THEREOF Radionetics Oncology, Inc. (US) 2025-08-13 — — EP disclosed
WO-2024077006-A1 FOLLICLE-STIMULATING HORMONE RECEPTOR (FSHR) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. (US) 2024-04-11 — — WO disclosed
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