SCHEMBL30759474

SCHEMBL30759474

COc1cc2c(cc1Br)-c1c(c(C(=O)O)nn1-c1cc(Cl)cc(Cl)c1)OC2

nearest known ligand 0.34

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 3/20 0.34
▸ HTT P42858 2/20 0.34
▸ CCNA2 P20248 1/20 0.33
▸ CDK2 P24941 1/20 0.33
▸ CCNA1 P78396 1/20 0.33
▸ CYP3A4 P08684 1/20 0.33
▸ CYP1A2 P05177 1/20 0.33
▸ HIF1A Q16665 1/20 0.33
▸ NOTUM Q6P988 2/20 0.33
▸ LMNA P02545 1/20 0.32
▸ HTR2A P28223 2/20 0.31
▸ HTR2C P28335 2/20 0.31
▸ HTR2B P41595 1/20 0.31
▸ MEN1 O00255 1/20 0.31
▸ KMT2A Q03164 1/20 0.31
▸ L3MBTL1 Q9Y468 1/20 0.31
▸ APP P05067 1/20 0.31
▸ KDM4E B2RXH2 1/20 0.31
▸ PTGS2 P35354 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27117850 1.00 MAPT (0.34) MAPTHTTCCNA2CDK2CCNA1
SCHEMBL31236960 0.91 CYP1A2 (0.33) MAPTCCNA2CDK2CCNA1CYP1A2
SCHEMBL30759541 0.88 L3MBTL1 (0.39) MAPTCCNA2CDK2CCNA1LMNA
SCHEMBL27117828 0.88 L3MBTL1 (0.39) MAPTCCNA2CDK2CCNA1LMNA
SCHEMBL30759577 0.82 CCNA2 (0.43) CCNA2CDK2CCNA1CYP1A2HIF1A
SCHEMBL27119370 0.82 CCNA2 (0.43) CCNA2CDK2CCNA1CYP1A2HIF1A
SCHEMBL27118754 0.82 CA12 (0.39) CCNA2CDK2CCNA1CYP1A2HIF1A
SCHEMBL27117858 0.82 GRM5 (0.38) KMT2A
SCHEMBL30759571 0.82 GRM5 (0.38) KMT2A
SCHEMBL30759570 0.81 CYP11B2 (0.32) CCNA2CDK2CCNA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260008783-A1 MODULATORS OF FSHR AND USES THEREOF GEDEON RICHTER PLC (HU) 2026-01-08 — — US disclosed
EP-4577206-A2 NOVEL MODULATORS OF FSHR AND USES THEREOF Celmatix Inc. (US) 2025-07-02 — — EP disclosed
WO-2024044778-A2 NOVEL MODULATORS OF FSHR AND USES THEREOF CELMATIX INC. (US) 2024-02-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008783-A1 MODULATORS OF FSHR AND USES THEREOF FSHR, GNRHR, LHCGR MAPT 4861/4885HTT 2554/4885CCNA2 2070/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback