Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.33 |
| ▸ | CDK2 | P24941 | 3/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.31 |
| ▸ | PIK3R2 | O00459 | 2/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.31 |
| ▸ | PIK3R5 | Q8WYR1 | 2/20 | 0.31 |
| ▸ | PIK3R3 | Q92569 | 2/20 | 0.31 |
| ▸ | ESRRB | O95718 | 2/20 | 0.31 |
| ▸ | ESRRA | P11474 | 2/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30885869 | 0.87 | CCNA2 (0.39) | CYP1A2HIF1ANR1H4ALDH1A1CCNA2 | |
| SCHEMBL17381608 | 0.87 | CCNA2 (0.39) | CYP1A2HIF1ANR1H4ALDH1A1CCNA2 | |
| SCHEMBL17385521 | 0.85 | L3MBTL1 (0.42) | CYP1A2KDM4EALDH1A1CCNA2CDK2 | |
| SCHEMBL31236979 | 0.78 | CCNA2 (0.39) | CYP1A2HIF1ACCNA2CDK2CCNA1 | |
| SCHEMBL31236976 | 0.78 | CCNA2 (0.39) | CYP1A2HIF1ACCNA2CDK2CCNA1 | |
| SCHEMBL30886155 | 0.77 | CCNA2 (0.38) | CYP1A2HIF1AALDH1A1PTGS2CCNA2 | |
| SCHEMBL17381996 | 0.76 | CCNA2 (0.46) | KDM4EALDH1A1CCNA2CDK2CCNA1 | |
| SCHEMBL17382365 | 0.76 | CCNA2 (0.39) | NR1H4CCNA2CDK2CCNA1PIK3CD | |
| SCHEMBL17381607 | 0.75 | CCNA2 (0.43) | KDM4EALDH1A1CCNA2CDK2CCNA1 | |
| SCHEMBL29538955 | 0.75 | CCNA2 (0.43) | KDM4EALDH1A1CCNA2CDK2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015196335-A1 | PYRAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF | TOCOPHERX, INC. (US) | 2015-12-30 | — | — | WO | disclosed |