Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | RIPK2 | O43353 | 6/20 | 0.33 |
| ▸ | KDR | P35968 | 6/20 | 0.33 |
| ▸ | LCK | P06239 | 5/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 5/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | FASN | P49327 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | CCNC | P24863 | 1/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24233949 | 0.81 | FFAR1 (0.35) | ALOX5APFEN1RIPK2KDRLCK | |
| SCHEMBL24366781 | 0.81 | FFAR1 (0.35) | ALOX5APFEN1RIPK2KDRLCK | |
| SCHEMBL31017209 | 0.72 | FFAR1 (0.36) | ALOX5APFEN1RIPK2KDRLCK | |
| SCHEMBL31500084 | 0.72 | CHRNB4 (0.45) | RIPK2KDRLCKTGFBR1FASN | |
| SCHEMBL24367106 | 0.70 | CHRNB4 (0.42) | ALDH1A1MCL1 | |
| SCHEMBL24365301 | 0.70 | DYRK1A (0.43) | TGFBR1 | |
| SCHEMBL28048502 | 0.69 | ALDH1A1 (0.54) | ALOX5APFEN1RIPK2KDRLCK | |
| SCHEMBL31017197 | 0.68 | TGFBR1 (0.36) | ALOX5APFEN1RIPK2KDRLCK | |
| SCHEMBL30886220 | 0.66 | DYRK1A (0.32) | RIPK2ALDH1A1HSD17B10 | |
| SCHEMBL17508092 | 0.65 | FASN (0.46) | RIPK2KDRLCKTGFBR1FASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118047793-A | Pyridine derivative and application thereof | 成都百裕制药股份有限公司 | 2024-05-17 | — | — | CN | disclosed |