Sugi Predict

Sugi Predict / Compounds / SCHEMBL30887320

SCHEMBL30887320

SCHEMBL30887320

CC[C@H](C)[C@H](NC(=O)[C@H](COC(C)(C)C)NC(=O)[C@H](Cc1ccc(OC(C)(C)C)cc1)NC(=O)[C@H](CC(=O)OC(C)(C)C)NC(=O)[C@H](COC(C)(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(=O)NC(c1ccccc1)(c1ccccc1)c1ccccc1)NC(=O)C(C)(C)NC(=O)[C@H](Cc1ccc(OC(C)(C)C)cc1)NC(=O)OC(C)(C)C)[C@@H](C)OC(C)(C)C)[C@@H](C)OC(C)(C)C)C(=O)N[C@@](C)(CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)OC(C)(C)C)C(=O)N[C@@H](CCCCNC(=O)OC(C)(C)C)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ PSEN1 P49768 15/20 0.44
▸ PSEN2 P49810 15/20 0.44
▸ APH1B Q8WW43 15/20 0.44
▸ NCSTN Q92542 15/20 0.44
▸ APH1A Q96BI3 15/20 0.44
▸ PSENEN Q9NZ42 15/20 0.44
▸ GLP1R P43220 2/20 0.43
▸ GCGR P47871 1/20 0.43
▸ GIPR P48546 1/20 0.43
▸ OPRM1 P35372 3/20 0.40
▸ OPRD1 P41143 3/20 0.40
▸ OPRK1 P41145 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30887322 0.98 GLP1R (0.44) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL30543486 0.93 OPRM1 (0.46) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL38651798 0.93 OPRM1 (0.46) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL38651875 0.93 OPRM1 (0.46) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL31114335 0.93 PSEN1 (0.47) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL30887319 0.92 PSEN1 (0.43) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL30543483 0.92 OPRM1 (0.45) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL30543487 0.92 OPRM1 (0.45) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL30852879 0.92 OPRM1 (0.44) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL30543477 0.92 OPRM1 (0.44) PSEN1PSEN2APH1BNCSTNAPH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119661654-A Polypeptide with modified structure and application thereof 广东众生睿创生物科技有限公司 2025-03-21 — — CN disclosed
CN-119656289-A Polypeptide with modified structure and application thereof 广东众生睿创生物科技有限公司 2025-03-21 — — CN disclosed
CN-118056839-B Polypeptide with modified structure and application thereof 广东众生睿创生物科技有限公司 2024-11-29 — — CN disclosed
WO-2024153091-A1 POLYPEPTIDE HAVING MODIFIED STRUCTURE AND USE THEREOF 广东众生睿创生物科技有限公司 2024-07-25 — — WO disclosed
WO-2024153089-A1 MULTI-TARGET AND LONG-ACTING POLYPEPTIDE AGONIST 广东众生睿创生物科技有限公司 2024-07-25 — — WO disclosed
CN-118056839-A Polypeptide with modified structure and application thereof 广东众生睿创生物科技有限公司 2024-05-21 — — CN disclosed
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