SCHEMBL30543486

SCHEMBL30543486

CC[C@H](C)[C@H](NC(=O)[C@H](CCCCNC(=O)OC(C)(C)C)NC(=O)[C@H](CC(=O)OC(C)(C)C)NC(=O)[C@H](CC(C)C)NC(=O)C(C)(C)NC(=O)[C@@H](NC(=O)[C@H](COC(C)(C)C)NC(=O)[C@H](Cc1ccc(OC(C)(C)C)cc1)NC(=O)[C@H](CC(=O)OC(C)(C)C)NC(=O)[C@H](COC(C)(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)C(C)(C)NC(=O)[C@H](Cc1ccc(OC(C)(C)C)cc1)NC(=O)OC(C)(C)C)[C@@H](C)OC(C)(C)C)[C@@H](C)OC(C)(C)C)[C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)NC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ OPRM1 P35372 5/20 0.46
▸ OPRD1 P41143 5/20 0.46
▸ OPRK1 P41145 5/20 0.46
▸ PSEN1 P49768 9/20 0.44
▸ PSEN2 P49810 9/20 0.44
▸ APH1B Q8WW43 9/20 0.44
▸ NCSTN Q92542 9/20 0.44
▸ APH1A Q96BI3 9/20 0.44
▸ PSENEN Q9NZ42 9/20 0.44
▸ GLP1R P43220 6/20 0.42
▸ GCGR P47871 1/20 0.42
▸ GIPR P48546 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38651798 1.00 OPRM1 (0.46) OPRM1OPRD1OPRK1PSEN1PSEN2
SCHEMBL38651875 1.00 OPRM1 (0.46) OPRM1OPRD1OPRK1PSEN1PSEN2
SCHEMBL30543477 0.98 OPRM1 (0.44) OPRM1OPRD1OPRK1PSEN1PSEN2
SCHEMBL30543483 0.98 OPRM1 (0.45) OPRM1OPRD1OPRK1PSEN1PSEN2
SCHEMBL30543487 0.98 OPRM1 (0.45) OPRM1OPRD1OPRK1PSEN1PSEN2
SCHEMBL30543484 0.98 OPRM1 (0.44) OPRM1OPRD1OPRK1PSEN1PSEN2
SCHEMBL30892071 0.96 OPRM1 (0.44) OPRM1OPRD1OPRK1PSEN1PSEN2
SCHEMBL30852879 0.96 OPRM1 (0.44) OPRM1OPRD1OPRK1PSEN1PSEN2
SCHEMBL30887322 0.95 GLP1R (0.44) OPRM1OPRD1OPRK1PSEN1PSEN2
SCHEMBL30543485 0.94 OPRM1 (0.43) OPRM1OPRD1OPRK1PSEN1PSEN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119350471-A Tenipout peptide synthesis method 中肽生化有限公司 2025-01-24 — — CN claimed
CN-119219745-A Preparation of tel method of poisein 深圳翰宇药业股份有限公司 2024-12-31 — — CN claimed
WO-2025130972-A1 SYNTHETIC METHOD FOR TIRZEPATIDE 深圳翰宇药业股份有限公司 2025-06-26 — — WO disclosed
CN-119350471-B Tenipout peptide synthesis method 中肽生化有限公司 2025-04-25 — — CN disclosed
CN-119350471-A Tenipout peptide synthesis method 中肽生化有限公司 2025-01-24 — — CN disclosed
US-20250019410-A1 PROCESS FOR THE PREPARATION OF TIRZEPATIDE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) 2025-01-16 — — US disclosed
CN-119219745-A Preparation of tel method of poisein 深圳翰宇药业股份有限公司 2024-12-31 — — CN disclosed
CN-117106055-A Synthesis method of telipopeptide 杭州思诺达医药科技有限责任公司 2023-11-24 — — CN disclosed
US-20230241178-A1 LONG ACTING GLP-1/GIP DUAL AGONISTS SUN PHARMACEUTICAL IND LTD (IN) 2023-08-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230241178-A1 LONG ACTING GLP-1/GIP DUAL AGONISTS GLP1R, GIPR, GPR119 OPRM1 1258/4885OPRD1 923/4885OPRK1 861/4885
US-20250019410-A1 PROCESS FOR THE PREPARATION OF TIRZEPATIDE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF SYK, TREH, QDPR OPRM1 4271/4885OPRD1 1919/4885OPRK1 3125/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback