Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 9/20 | 0.36 |
| ▸ | CCND1 | P24385 | 8/20 | 0.36 |
| ▸ | CCND3 | P30281 | 7/20 | 0.36 |
| ▸ | CDK6 | Q00534 | 7/20 | 0.36 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.35 |
| ▸ | CLK1 | P49759 | 1/20 | 0.35 |
| ▸ | CLK2 | P49760 | 1/20 | 0.35 |
| ▸ | CLK3 | P49761 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | DYRK4 | Q9NR20 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21522918 | 1.00 | CDK4 (0.36) | CDK4CCND1CCND3CDK6CSNK1E | |
| SCHEMBL15826117 | 0.79 | ADORA3 (0.36) | CYP11B1CYP11B2ALOX15HTT | |
| SCHEMBL29827557 | 0.73 | FABP4 (0.48) | CDK4CCND1CDK6CSNK1ECLK1 | |
| SCHEMBL8130706 | 0.73 | CYP11B1 (0.45) | CSNK1ECLK1CLK2CLK3GSK3B | |
| SCHEMBL12853410 | 0.73 | FABP4 (0.48) | CDK4CCND1CDK6CSNK1ECLK1 | |
| SCHEMBL9081176 | 0.73 | CCNT1 (0.49) | CDK4CCND1CCND3CDK6CSNK1E | |
| SCHEMBL15742079 | 0.72 | EGFR (0.42) | EGFR | |
| SCHEMBL16806047 | 0.71 | KDM4E (0.51) | CYP11B1CYP11B2HDAC1ALOX15HTT | |
| SCHEMBL2490112 | 0.71 | PLK4 (0.40) | CDK4CDK6HDAC1CDK1CCNB1 | |
| SCHEMBL30309559 | 0.71 | PLK4 (0.40) | CDK4CDK6HDAC1CDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250129104-A1 | 7H-PYRROLO[2,3-D]PYRIMIDINES AND PREPARATION AND USES THEREOF | TENARX, INC. | 2025-04-24 | — | — | US | disclosed |
| CN-118286225-A | 2-Amino-pyridine or 2-amino-pyrimidine derivatives as cyclin dependent kinase inhibitors | 辉瑞公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-112313219-B | 2-Amino-pyridine or 2-amino-pyrimidine derivatives as cyclin dependent kinase inhibitors | 辉瑞公司 | 2024-04-26 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250129104-A1 | 7H-PYRROLO[2,3-D]PYRIMIDINES AND PREPARATION AND USES THEREOF | DYRK1A, DYRK1B, DYRK2 | CDK4 316/4885CCND1 463/4885CCND3 342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.