Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 4/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20607545 | 0.86 | AOC3 (0.54) | AOC3GPR119ACHEGRIA1CXCR2 | |
| SCHEMBL28402460 | 0.75 | AOC3 (0.39) | AOC3 | |
| SCHEMBL31652066 | 0.74 | POLB (0.45) | GPR119GRM5GRM1MAPT | |
| SCHEMBL2292608 | 0.70 | USP2 (0.52) | GPR119 | |
| SCHEMBL11366665 | 0.70 | POLB (0.54) | GPR119ACHE | |
| SCHEMBL30798259 | 0.70 | GPR119 (0.47) | GPR119ACHE | |
| SCHEMBL670559 | 0.68 | ACHE (0.48) | GPR119ACHECXCR2MAPT | |
| SCHEMBL22993252 | 0.67 | ESR2 (0.53) | MAPT | |
| SCHEMBL22993223 | 0.67 | ESR2 (0.53) | MAPT | |
| SCHEMBL29391455 | 0.67 | ESR2 (0.53) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111196806-B | Guanidine derivative and application thereof | 广东东阳光药业股份有限公司 | 2024-04-26 | — | — | CN | disclosed |