Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 11/20 | 0.37 |
| ▸ | TIPARP | Q7Z3E1 | 2/20 | 0.36 |
| ▸ | NAMPT | P43490 | 3/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30889382 | 1.00 | AOC3 (0.37) | AOC3TIPARPNAMPTHDAC1HDAC2 | |
| SCHEMBL30889387 | 0.78 | AOC3 (0.36) | AOC3 | |
| SCHEMBL30889374 | 0.74 | AOC3 (0.40) | AOC3 | |
| SCHEMBL30889375 | 0.74 | AOC3 (0.40) | AOC3 | |
| SCHEMBL20607543 | 0.71 | HTR2C (0.50) | — | |
| SCHEMBL28402460 | 0.70 | AOC3 (0.39) | AOC3 | |
| SCHEMBL30889378 | 0.66 | AOC3 (0.48) | AOC3 | |
| SCHEMBL29198420 | 0.64 | AOC3 (0.48) | AOC3 | |
| SCHEMBL501250 | 0.63 | — | — | |
| SCHEMBL28923808 | 0.63 | SIGMAR1 (0.46) | TIPARPNAMPTHDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111196806-B | Guanidine derivative and application thereof | 广东东阳光药业股份有限公司 | 2024-04-26 | — | — | CN | disclosed |