Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | MLNR | O43193 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.36 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3089649 | 0.94 | OPRM1 (0.44) | SLC6A2SLC6A3OPRM1SLC6A4KCNH2 | |
| SCHEMBL3091540 | 0.93 | SLC6A2 (0.43) | SLC6A2SLC6A3OPRM1SLC6A4HTR6 | |
| SCHEMBL3089729 | 0.91 | OPRM1 (0.43) | SLC6A2SLC6A3OPRM1SLC6A4TACR1 | |
| SCHEMBL3097551 | 0.90 | IDH1 (0.40) | SLC6A2SLC6A3OPRM1SLC6A4TACR1 | |
| SCHEMBL3088108 | 0.90 | SLC6A4 (0.41) | SLC6A2SLC6A3OPRM1SLC6A4TACR1 | |
| SCHEMBL3091600 | 0.88 | OPRM1 (0.44) | SLC6A2SLC6A3OPRM1SLC6A4KCNH2 | |
| SCHEMBL3083015 | 0.87 | OPRM1 (0.43) | SLC6A2SLC6A3OPRM1SLC6A4KCNH2 | |
| SCHEMBL3094952 | 0.84 | OPRM1 (0.43) | SLC6A2SLC6A3OPRM1SLC6A4KCNH2 | |
| SCHEMBL3083067 | 0.83 | OPRM1 (0.46) | OPRM1SLC6A4TACR1MLNRALDH1A1 | |
| SCHEMBL3083240 | 0.82 | OPRM1 (0.39) | SLC6A2SLC6A3OPRM1SLC6A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100234427-A1 | 1-PHENETHYLPIPERIDINE DERIVATIVES AND THEIR USE AS OPIOID RECEPTOR LIGANDS | NEUROSEARCH A/S (DK) | 2010-09-16 | — | — | US | claimed |
| EP-1987001-B1 | 1-PHENETHYLPIPERIDINE DERIVATIVES AND THEIR USE AS OPIOID RECEPTOR LIGANDS | NEUROSEARCH AS (DK) | 2010-05-05 | — | — | EP | claimed |
| EP-1987001-A1 | 1-PHENETHYLPIPERIDINE DERIVATIVES AND THEIR USE AS OPIOID RECEPTOR LIGANDS | NeuroSearch A/S (DK) | 2008-11-05 | — | — | EP | claimed |
| WO-2007093603-A1 | 1-PHENETHYLPIPERIDINE DERIVATIVES AND THEIR USE AS OPIOID RECEPTOR LIGANDS | NEUROSEARCH A/S (DK) | 2007-08-23 | — | — | WO | claimed |
| US-20100234427-A1 | 1-PHENETHYLPIPERIDINE DERIVATIVES AND THEIR USE AS OPIOID RECEPTOR LIGANDS | NEUROSEARCH A/S (DK) | 2010-09-16 | — | — | US | disclosed |
| EP-1987001-B1 | 1-PHENETHYLPIPERIDINE DERIVATIVES AND THEIR USE AS OPIOID RECEPTOR LIGANDS | NEUROSEARCH AS (DK) | 2010-05-05 | — | — | EP | disclosed |
| EP-1987001-A1 | 1-PHENETHYLPIPERIDINE DERIVATIVES AND THEIR USE AS OPIOID RECEPTOR LIGANDS | NeuroSearch A/S (DK) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007093603-A1 | 1-PHENETHYLPIPERIDINE DERIVATIVES AND THEIR USE AS OPIOID RECEPTOR LIGANDS | NEUROSEARCH A/S (DK) | 2007-08-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234427-A1 | 1-PHENETHYLPIPERIDINE DERIVATIVES AND THEIR USE AS OPIOID RECEPTOR LIGANDS | OPRL1, OPRM1, OPRK1 | SLC6A2 521/4885SLC6A3 501/4885OPRM1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.