Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | GPR183 | P32249 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29888814 | 0.87 | ALDH1A1 (0.49) | MAPTALDH1A1LMNAPARP1KCNH2 | |
| SCHEMBL16013943 | 0.86 | ALDH1A1 (0.48) | MAPTALDH1A1LMNAKCNH2GPR119 | |
| SCHEMBL22179574 | 0.85 | ALDH1A1 (0.51) | MAPTALDH1A1LMNAPARP1THRB | |
| SCHEMBL31548463 | 0.85 | ALDH1A1 (0.51) | MAPTALDH1A1LMNAPARP1THRB | |
| SCHEMBL31639802 | 0.85 | ALDH1A1 (0.44) | MAPTALDH1A1LMNAGPR119 | |
| SCHEMBL2448576 | 0.84 | MAPT (0.64) | MAPTALDH1A1LMNAKCNH2GPR119 | |
| SCHEMBL27406158 | 0.84 | PARP1 (0.42) | PARP1GPR119RORCHDAC2HDAC1 | |
| SCHEMBL30890214 | 0.83 | HDAC2 (0.41) | PARP1GPR119RORCHDAC2HDAC1 | |
| SCHEMBL27406159 | 0.83 | USP30 (0.43) | PARP1GPR119RORCHDAC2HDAC1 | |
| SCHEMBL12005382 | 0.80 | MAPT (0.71) | MAPTALDH1A1LMNAGPR119EGLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025137605-A1 | COMPOUNDS FOR TARGETED DEGRADATION OF PROTO-ONCOGENE TYROSINE PROTEIN KINASE RECEPTOR | C4 THERAPEUTICS, INC. (US) | 2025-06-26 | — | — | WO | disclosed |
| WO-2024108009-A1 | DYRK/CLK PROTACS AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2024-05-23 | — | — | WO | disclosed |