Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 5/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.40 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | GPR183 | P32249 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 2/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27406158 | 0.88 | PARP1 (0.42) | HDAC2HDAC1PARP1GPR119EGLN2 | |
| SCHEMBL27406159 | 0.87 | USP30 (0.43) | HDAC2HDAC1PARP1GPR119EGLN2 | |
| SCHEMBL18755012 | 0.86 | NR1H2 (0.41) | HDAC2HDAC1PARP1NR1H2GPR119 | |
| SCHEMBL16013883 | 0.85 | NR1H2 (0.41) | HDAC2HDAC1PARP1NR1H2GPR119 | |
| SCHEMBL31548466 | 0.84 | NR1H2 (0.46) | HDAC2HDAC1PARP1NR1H2GPR119 | |
| SCHEMBL22165053 | 0.84 | NR1H2 (0.46) | HDAC2HDAC1PARP1NR1H2GPR119 | |
| SCHEMBL30890210 | 0.83 | MAPT (0.48) | HDAC2HDAC1PARP1NR1H2GPR119 | |
| SCHEMBL31639563 | 0.83 | DPP4 (0.44) | GPR119DPP4ALOX5APFEN1 | |
| SCHEMBL2445935 | 0.83 | GPR119 (0.49) | NR1H2GPR119DPP4 | |
| SCHEMBL27187883 | 0.80 | USP30 (0.40) | HDAC2HDAC1PARP1NR1H2GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025137605-A1 | COMPOUNDS FOR TARGETED DEGRADATION OF PROTO-ONCOGENE TYROSINE PROTEIN KINASE RECEPTOR | C4 THERAPEUTICS, INC. (US) | 2025-06-26 | — | — | WO | disclosed |
| WO-2024108009-A1 | DYRK/CLK PROTACS AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2024-05-23 | — | — | WO | disclosed |