⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11552463 | 0.72 | ADRA2A (0.34) | — | |
| SCHEMBL12972359 | 0.69 | — | — | |
| SCHEMBL962172 | 0.69 | — | — | |
| SCHEMBL27686659 | 0.69 | — | — | |
| SCHEMBL27380976 | 0.68 | KDM4E (0.34) | — | |
| SCHEMBL965609 | 0.66 | THRB (0.31) | — | |
| SCHEMBL28174536 | 0.65 | — | — | |
| SCHEMBL8656142 | 0.65 | — | — | |
| SCHEMBL2535453 | 0.65 | — | — | |
| SCHEMBL28275692 | 0.64 | KDM4E (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7834190-B2 | Process for production of optically active-3-amino-2-hydroxypropionic cyclopropylamide derivatives and salts thereof | KANEKA CORPORATION (JP) | 2010-11-16 | — | — | US | claimed |
| US-20100048909-A1 | Process for production of optically active-3-amino-2-hydroxypropionic cyclopropylamide derivatives and salts thereof | KANEKA CORPORATION | 2010-02-25 | — | — | US | claimed |
| CN-100548671-C | Transparent decoratable multilayer film | DEGUSSA (DE) | 2009-10-14 | — | — | CN | claimed |
| EP-2039689-A1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE 3-AMINO-2 -HYDROXYPROPIONIC CYCLOPROPYLAMIDE DERIVATIVES AND SALTS THEREOF | Kaneka Corporation (JP) | 2009-03-25 | — | — | EP | claimed |
| CN-1824498-A | Transparent decoratable multilayer film | DEGUSSA (DE) | 2006-08-30 | — | — | CN | claimed |
| CN-1053678-C | Thermoplastic elastomer based on polyolefin-polyacrylate | OPTATECH CORP (FI) | 2000-06-21 | — | — | CN | claimed |
| CN-109438434-A | A kind of 2- cyanoimino thiazolidine compounds of the ring containing oxazole and its preparation method and application | 华南农业大学 | 2019-03-08 | — | — | CN | disclosed |
| EP-2719688-B1 | Process for producing tetrazolyloxime derivatives | NIPPON SODA CO (JP) | 2016-07-20 | — | — | EP | disclosed |
| EP-2719686-B1 | Process to halogenate a picoline derivative | NIPPON SODA CO (JP) | 2015-12-02 | — | — | EP | disclosed |
| EP-2719687-B1 | Process to make a bromopicoline derivative | NIPPON SODA CO (JP) | 2015-09-16 | — | — | EP | disclosed |
| US-9018385-B2 | Compound containing pyridine ring and method for producing halogenated picoline derivative and tetrazolyloxime derivative | NIPPON SODA CO., LTD. (JP) | 2015-04-28 | — | — | US | disclosed |
| US-9012653-B2 | Compound containing pyridine ring and method for producing halogenated picoline derivative and tetrazolyloxime derivative | NIPPON SODA CO., LTD. (JP) | 2015-04-21 | — | — | US | disclosed |
| US-9000178-B2 | Compound containing pyridine ring and method for producing halogenated picoline derivative and tetrazolyloxime derivative | NIPPON SODA CO., LTD. (JP) | 2015-04-07 | — | — | US | disclosed |
| US-6020507-A | Synthesis of paclitaxel from baccatin III by protection of the 7-hydroxyl of baccatin III using a strong base and an electrophile | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-02-01 | — | — | US | disclosed |
| WO-1999045001-A1 | SYNTHESIS OF PACLITAXEL BACCATIN III BY PROTECTING THE 7-HYDROXYL USING A STRONG BASE AND AN ELECTROPHILE | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-09-10 | — | — | WO | disclosed |
| CN-1125575-A | Adhesion receptor antagonists | MERCK PATENT GMBH (DE) | 1996-07-03 | — | — | CN | disclosed |
| US-4018782-A | 1-OXAPENICILLINS, ANTIBIOTICS | QUEEN'S UNIVERSITY (CA) | 1977-04-19 | — | — | US | disclosed |
| US-3985764-A | REACTING CHLORINATED ESTERS OF ANHYDROBENZYLPENICILLIN WITH ALUMINA OR SILICA GEL | QUEEN'S UNIVERSITY (CA) | 1976-10-12 | — | — | US | disclosed |
| US-3950352-A | ANTIBIOTICS, OXAPENICILLINS | QUEEN'S UNIVERSITY (CA) | 1976-04-13 | — | — | US | disclosed |
| US-3948927-A | ANTIBIOTIC INTERMEDIATE | QUEEN'S UNIVERSITY (CA) | 1976-04-06 | — | — | US | disclosed |