Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25370697 | 0.85 | ALDH1A1 (0.54) | ALDH1A1MAPTLMNATHRBKMT2A | |
| SCHEMBL30890278 | 0.84 | ALDH1A1 (0.52) | ALDH1A1MAPTLMNATHRBKMT2A | |
| SCHEMBL27404998 | 0.84 | ALDH1A1 (0.52) | ALDH1A1MAPTLMNATHRBKMT2A | |
| SCHEMBL30890277 | 0.84 | ALDH1A1 (0.52) | ALDH1A1MAPTLMNATHRBKMT2A | |
| SCHEMBL31485106 | 0.83 | ALDH1A1 (0.51) | ALDH1A1MAPTLMNATHRBKMT2A | |
| SCHEMBL19211105 | 0.83 | ALDH1A1 (0.51) | ALDH1A1MAPTLMNATHRBKMT2A | |
| SCHEMBL29577097 | 0.83 | ALDH1A1 (0.51) | ALDH1A1MAPTLMNATHRBKMT2A | |
| SCHEMBL2088339 | 0.83 | ALDH1A1 (0.52) | ALDH1A1MAPTLMNATHRBKMT2A | |
| SCHEMBL30890364 | 0.82 | NR1H2 (0.46) | GPR119USP30HRH3SCN9ASMN1; SMN2 | |
| SCHEMBL21848199 | 0.82 | MAPT (0.62) | ALDH1A1MAPTLMNAKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024227104-A1 | BIFUNCTIONAL COMPOUNDS FOR DEGRADING BRAF VIA UBIQUITIN PROTEOSOME PATHWAY | NURIX THERAPEUTICS, INC. (US) | 2024-10-31 | — | — | WO | disclosed |
| WO-2024108009-A1 | DYRK/CLK PROTACS AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2024-05-23 | — | — | WO | disclosed |